武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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RhoA-GTP

Anti-RhoA-GTP Mouse Monoclonal Antibody
5/5

$4,800.00

货号:26904

规格: 30 微升

库存状态:In Stock

           产品描述          
产品名称:   RhoA-GTP 小鼠单抗
货号:   26904
规格:   30 µL
基因符号:   RHOA
描述:   RhoA-GTP 小鼠单抗
背景:   Small GTPases are a super-family of cellular signaling regulators. RhoA belongs to the Rho sub-family of GTPases. Rho proteins play critical roles in many actin cytoskeleton- dependent processes including platelet aggregation, cell motility, contraction, and cytokinesis. It regulates the formation of stress fibers and focal adhesions in fibroblasts and Ca 2+ sensitivity of smooth muscle contraction.
免疫原:   Recombinant full length protein of active RhoA
经过测试的应用:   IP, IHC and IF (Not applicable for WB since WB denatures the GTPase)
推荐稀释比:   IP: 1 µg for 1~2 mg total cellular proteinsIHC, IF: 1:50-1:250
Concentration:   1 mg/ml
种属反应性:   Mouse
形式:   Liquid
克隆性:   Monoclonal
亚型:   IgG2b
纯化:   Purified from ascites
成分:  PBS (without Mg 2+ and Ca 2+ ), pH 7.4, 150 mM NaCl, 50% glycerol
种属反应性:  RhoA monoclonal antibody recognizes active RhoA from vertebrates.
储存条件:   Store at -20°C. Avoid repeated freezing and thawing
免疫沉淀/蛋白质印迹:  image.pngIP/WB Analysis of Active RhoA Protein.Purified recombinant RhoA proteins were loaded with GDP (lane 1) or GTPγS (lane 2). These proteins were immunoprecipitated with anti-RhoA-GTP monoclonal antibody (货号:   26904). After SDS/PAGE, the membrane filter was probed with anti-RhoA 小鼠单抗 (货号:   26007).
           引用文献          

<table>
<tbody>
<tr><td><strong>001.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/37225434/” target=”_blank” rel=”noopener”>Ogt Deficiency Induces Abnormal Cerebellar Function and Behavioral Deficits of Adult Mice through Modulating RhoA/ROCK Signaling</a><br/>J Neurosci. 2023 &emsp;&emsp;PMID:&nbsp;37225434</td><tr/>
<tr><td><strong>002.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/36284029/” target=”_blank” rel=”noopener”>Critical role of mitogen-inducible gene 6 in restraining endothelial cell permeability to maintain vascular homeostasis</a><br/>J Cell Commun Signal. 2023 &emsp;&emsp;PMID:&nbsp; 36477766</td><tr/>
<tr><td><strong>003.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967383/” target=”_blank” rel=”noopener”>Reducing GEF-H1 Expression Inhibits Renal Cyst Formation, Inflammation, and Fibrosis via RhoA Signaling in Nephronophthisis</a><br/>Int J Mol Sci. 2023 &emsp;&emsp;PMID:&nbsp; 36834937</td><tr/>
<tr><td><strong>004.&emsp;</strong><a href=”https://www.researchsquare.com/article/rs-2508957/v1″ target=”_blank” rel=”noopener”>Junctional Force Patterning drives both Positional and Orientational Order in Auditory Epithelia</a><br/>Research Square. 2023 &emsp;&emsp;PMID:&nbsp;</td><tr/>
<tr><td><strong>005.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/36379207/” target=”_blank” rel=”noopener”>CD16+ fibroblasts foster a trastuzumab-refractory microenvironment that is reversed by VAV2 inhibition</a><br/>Cancer Cell. 2022&emsp;&emsp;PMID:&nbsp;36379207</td><tr/>
<tr><td><strong>006.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/35460881/” target=”_blank” rel=”noopener”>BKM120 alters the migration of doublecortin-positive cells in the dentate gyrus of mice</a><br/>Pharmacol Res. 2022&emsp;&emsp;PMID:&nbsp;35460881</td><tr/>
<tr><td><strong>007.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/36323321/” target=”_blank” rel=”noopener”>Mechanosensitive brain tumor cells construct blood-tumor barrier to mask chemosensitivity</a><br/>Neuron. 2022&emsp;&emsp;PMID:&nbsp;36323321</td><tr/>
<tr><td><strong>008.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/36284029/” target=”_blank” rel=”noopener”>Critical role of mitogen-inducible gene 6 in restraining endothelial cell permeability to maintain vascular homeostasis</a><br/>J Cell Commun Signal. 2022&emsp;&emsp;PMID:&nbsp;36284029</td><tr/>
<tr><td><strong>009.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/36265882/” target=”_blank” rel=”noopener”>Cystic fibrosis macrophage function and clinical outcomes after elexacaftor/tezacaftor/ivacaftor</a><br/>Eur Respir J. 2022&emsp;&emsp;PMID:&nbsp;36265882</td><tr/>
<tr><td><strong>010.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/36001358/” target=”_blank” rel=”noopener”>ARHGEF15 in Sertoli cells contributes to germ cell development and testicular immune privilege</a><br/>Biol Reprod. 2022&emsp;&emsp;PMID:&nbsp;36001358</td><tr/>
<tr><td><strong>011.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/35074515/” target=”_blank” rel=”noopener”>Rac1 mediates cadherin-11 induced cellular pathogenic processes in aortic valve calcification</a><br/>Cardiovasc Pathol. 2022&emsp;&emsp;PMID:&nbsp;35074515</td><tr/>
<tr><td><strong>012.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/34528082/” target=”_blank” rel=”noopener”>Endothelial Poldip2 regulates sepsis-induced lung injury via Rho pathway activation</a><br/>Cardiovasc Res. 2022&emsp;&emsp;PMID:&nbsp;34528082</td><tr/>
<tr><td><strong>013.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/35306138/” target=”_blank” rel=”noopener”>IGF2BP2 promotes gastric cancer progression by regulating the IGF1R-RhoA-ROCK signaling pathway</a><br/>Cell Signal. 2022&emsp;&emsp;PMID:&nbsp;35306138</td><tr/>
<tr><td><strong>014.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/35367887/” target=” blank” rel=”noopener”>Long-term exposure to low concentrations of MC-LR induces blood-testis barrier damage through the RhoA/ROCK pathway</a><br/>Ecotoxicol Environ Saf. 2022&emsp;&emsp;PMID:&nbsp;35367887</td><tr/>
<tr><td><strong>015.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308268/” target=”_blank” rel=”noopener”>ARHGEF37 overexpression promotes extravasation and metastasis of hepatocellular carcinoma via directly activating Cdc42</a><br/>J Exp Clin Cancer Res. 2022&emsp;&emsp;PMID:&nbsp;35869555</td><tr/>
<tr><td><strong>016.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051212/” target=”_blank” rel=”noopener”>Hypoxia-activated neuropeptide Y/Y5 receptor/RhoA pathway triggers chromosomal instability and bone metastasis in Ewing sarcoma</a><br/>Nat Commun. 2022&emsp;&emsp;PMID:&nbsp;35484119</td><tr/>
<tr><td><strong>017.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993752″ target=”_blank” rel=”noopener”>Modulation of Mechanical Stress Mitigates Anti-Dsg3 Antibody-Induced Dissociation of Cell-Cell Adhesion</a><br/>Adv Biol (Weinh). 2021&emsp;&emsp;PMID:&nbsp;33724731</td><tr/>
<tr><td><strong>018.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576704/” target=”_blank” rel=”noopener”>MYO1B enhances colorectal cancer metastasis by promoting the F-actin rearrangement and focal adhesion assembly via RhoA/ROCK/FAK signaling</a><br/>Ann Transl Med. 2021&emsp;&emsp;PMID:&nbsp;34790749</td><tr/>
<tr><td><strong>019.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213848/” target=”_blank” rel=”noopener”>Glucocorticoid-mediated induction of caveolin-1 disrupts cytoskeletal organization.inhibits cell migration and re-epithelialization of non-healing wounds</a><br/>Commun Biol. 2021&emsp;&emsp;PMID:&nbsp;34145387</td><tr/>
<tr><td><strong>020.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276982/” target=”_blank” rel=”noopener”>Hydrostatic mechanical stress regulates growth and maturation of the atrioventricular valve</a><br/>Development. 2021&emsp;&emsp;PMID:&nbsp;34086041</td><tr/>
<tr><td><strong>021.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/33472844/” target=”_blank” rel=”noopener”>Oxygen regulates epithelial stem cell proliferation via RhoA-actomyosin-YAP/TAZ signal in mouse incisor</a><br/>Development. 2021&emsp;&emsp;PMID:&nbsp; 33472844</td><tr/>
<tr><td><strong>022.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/33792148/” target=”_blank” rel=”noopener”>ROCK inhibitor attenuates carbon blacks-induced pulmonary fibrosis in mice via Rho/ROCK/NF-kappa B pathway</a><br/>Environ Toxicol. 2021&emsp;&emsp;PMID:&nbsp;33792148</td><tr/>
<tr><td><strong>023.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703258/” target=”_blank” rel=”noopener”>BBS7–SHH Signaling Activity Regulates Primary Cilia for Periodontal Homeostasis</a><br/>Front Cell Dev Biol. 2021&emsp;&emsp;PMID:&nbsp;34957122</td><tr/>
<tr><td><strong>024.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081905/” target=”_blank” rel=”noopener”>Benzo(a)pyrene Enhanced Dermatophagoides Group 1 (Der f 1)-Induced TGFß1 Signaling Activation Through the Aryl Hydrocarbon Receptor-RhoA Axis in Asthma</a><br/>Front Immunol. 2021&emsp;&emsp;PMID:&nbsp;33936062</td><tr/>
<tr><td><strong>025.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000060/” target=”_blank” rel=”noopener”>Activin A and Cell-Surface GRP78 Are Novel Targetable RhoA Activators for Diabetic Kidney Disease</a><br/>Int J Mol Sci. 2021&emsp;&emsp;PMID:&nbsp;33799579</td><tr/>
<tr><td><strong>026.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/34166723/” target=” blank” rel=”noopener”>Modulation of proteoglycan receptor regulates RhoA/CRMP2 pathways and promotes axonal myelination</a><br/>Neurosci Lett. 2021&emsp;&emsp;PMID:&nbsp;34166723</td><tr/>
<tr><td><strong>027.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/34166723/” target=” blank” rel=”noopener”>Modulation of proteoglycan receptor regulates RhoA/CRMP2 pathways and promotes axonal myelination</a><br/>Neurosci Lett. 2021&emsp;&emsp;PMID:&nbsp;34166723</td><tr/>
<tr><td><strong>028.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423926″ target=”_blank” rel=”noopener”>Decreased Level of Exosomal miR-5121 Released from Microglia Suppresses Neurite Outgrowth and Synapse Recovery of Neurons Following Traumatic Brain Injury</a><br/>Neurotherapeutics. 2021&emsp;&emsp;PMID:&nbsp;33475953</td><tr/>
<tr><td><strong>029.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/34600176/” target=” blank” rel=”noopener”>The role of daurisoline treatment in hepatocellular carcinoma: Inhibiting vasculogenic mimicry formation and enhancing sensitivity to sorafenib</a><br/>Phytomedicine. 2021&emsp;&emsp;PMID:&nbsp;34600176</td><tr/>
<tr><td><strong>030.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058714/” target=”_blank” rel=”noopener”>MYBL2 disrupts the Hippo-YAP pathway and confers castration resistance and metastatic potential in prostate cancer</a><br/>Theranostics. 2021&emsp;&emsp;PMID:&nbsp;33897882</td><tr/>
<tr><td><strong>031.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/32903032/” target=”_blank” rel=”noopener”>Spatial locations of certain enzymes and transporters within preinvasive ductal epithelial cells predict human breast cancer recurrences</a><br/>Am J Physiol Cell Physiol. 2020&emsp;&emsp;PMID:&nbsp;32903032</td><tr/>
<tr><td><strong>032.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/34210880/” target=” blank” rel=”noopener”>Astrocytes close the critical period for visual plasticity</a><br/>bioRxiv. 2020&emsp;&emsp;PMID:&nbsp;34210880</td><tr/>
<tr><td><strong>033.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7548225″ target=”_blank” rel=”noopener”>ANLN Directly Interacts with RhoA to Promote Doxorubicin Resistance in Breast Cancer Cells</a><br/>Cancer Manag Res. 2020&emsp;&emsp;PMID:&nbsp;33116832</td><tr/>
<tr><td><strong>034.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/32579923/” target=”_blank” rel=”noopener”>Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration</a><br/>Cell Rep. 2020&emsp;&emsp;PMID:&nbsp;32579923</td><tr/>
<tr><td><strong>035.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/33378678/” target=” blank” rel=”noopener”>QUAKING Regulates Microexon Alternative Splicing of the Rho GTPase Pathway and Controls Microglia Homeostasis</a><br/>Cell Rep. 2020&emsp;&emsp;PMID:&nbsp;33378678</td><tr/>
<tr><td><strong>036.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021812/” target=”_blank” rel=”noopener”>Serotonin 5-HT4 receptor boosts functional maturation of dendritic spines via RhoA-dependent control of F-actin</a><br/>Commun Biol. 2020&emsp;&emsp;PMID:&nbsp;32060357</td><tr/>
<tr><td><strong>037.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/32428455/” target=” blank” rel=”noopener”>Ligand Binding to the Collagen VI Receptor Triggers a Talin-to-RhoA Switch that Regulates Receptor Endocytosis</a><br/>Dev Cell. 2020&emsp;&emsp;PMID:&nbsp;32428455</td><tr/>
<tr><td><strong>038.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928066/” target=”_blank” rel=”noopener”>europeptide Y/Y5 Receptor Pathway Stimulates Neuroblastoma Cell Motility Through RhoA Activation</a><br/>Front Cell Dev Biol. 2020&emsp;&emsp;PMID:&nbsp;33681186</td><tr/>
<tr><td><strong>039.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299196″ target=”_blank” rel=”noopener”>Arhgef5 Binds a-Dystrobrevin 1 and Regulates Neuromuscular Junction Integrity</a><br/>Front Mol Neurosci. 2020&emsp;&emsp;PMID:&nbsp;32587503</td><tr/>
<tr><td><strong>040.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335183/” target=”_blank” rel=”noopener”>Wnt-controlled sphingolipids modulate Anthrax Toxin Receptor palmitoylation to regulate oriented mitosis in zebrafishs</a><br/>Nat Commun. 2020&emsp;&emsp;PMID:&nbsp;32620775</td><tr/>
<tr><td><strong>041.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020796″ target=”_blank” rel=”noopener”>Dysregulation of Rac or Rho elicits death of motor neurons and activation of these GTPases is altered in the G93A mutant hSOD1 mouse model of amyotrophic lateral sclerosis</a><br/>Neurobiol Dis. 2020&emsp;&emsp;PMID:&nbsp;31931138</td><tr/>
<tr><td><strong>042.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549670/” target=”_blank” rel=”noopener”>Acute compressive stress activates RHO/ROCK-mediated cellular processes</a><br/>Small GTPases. 2020&emsp;&emsp;PMID:&nbsp;29455593</td><tr/>
<tr><td><strong>043.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246394/” target=” blank” rel=”noopener”>Actin Alpha 2 (ACTA2) Downregulation Inhibits Neural Stem Cell Migration through Rho GTPase Activation</a><br/>Stem Cells Int. 2020&emsp;&emsp;PMID:&nbsp;32508931</td><tr/>
<tr><td><strong>044.&emsp;</strong><a href=”https://www.jikm.or.kr/journal/view.php?doi=10. 22246/jikm. 2020.41.4.553″ target=”_blank” rel=”noopener”>Mitigative Effect of Sipjeondaebo-tang on RhoA Activation in Cold-Exposed Vascular Cells</a><br/>The Journal of Internal Korean Medicine. 2020&emsp;&emsp;PMID:&nbsp;https://www.jikm.or.kr/journal/view.php?doi=10. 22246/jikm. 2020.41.4.553</td><tr/>
<tr><td><strong>045.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787190/” target=”_blank” rel=”noopener”>Matrine inhibits the development and progression of ovarian cancer by repressing cancer associated phosphorylation signaling pathways</a><br/>Cell Death & Disease&#44;2019&emsp;&emsp;PMID:&nbsp;31601793</td><tr/>
<tr><td><strong>046.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554403/” target=”_blank” rel=”noopener”>The alteration of RhoA geranylgeranylation and Ras farnesylation breaks the integrity of the blood–testis barrier and results in hypospermatogenesis</a><br/>Cell Death Dis. 2019&emsp;&emsp;PMID:&nbsp;31171774</td><tr/>
<tr><td><strong>047.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/31530101/” target=” blank” rel=”noopener”>BK<sub>Ca</sub> compensates impaired coronary vasoreactivity through RhoA/ROCK pathway in hind-limb unweighted rats</a><br/>FASEB J. 2019&emsp;&emsp;PMID:&nbsp; 31530101</td><tr/>
<tr><td><strong>048.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/30374974/” target=” blank” rel=”noopener”>The role of sema4D in vasculogenic mimicry formation in non-small cell lung cancer and the underlying mechanisms</a><br/>Int J Cancer. 2019&emsp;&emsp;PMID:&nbsp; 30374974</td><tr/>
<tr><td><strong>049.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401351/” target=”_blank” rel=”noopener”>RhoA/ROCK Signaling Modulates Lineage Commitment of Mesenchymal Stem Cells in Asthma through Lef1</a><br/>J Allergy Clin Immunol. 2019&emsp;&emsp;PMID:&nbsp;30194990</td><tr/>
<tr><td><strong>050.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802501/” target=”_blank” rel=”noopener”>Claudin-2 suppresses GEF-H1.RHOA.and MRTF.thereby impacting proliferation and profibrotic phenotype of tubular cells</a><br/>J Biol Chem. 2019&emsp;&emsp;PMID:&nbsp;31481470</td><tr/>
<tr><td><strong>051.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/30609027/” target=”_blank” rel=”noopener”>Sensory plasticity of carotid body is correlated with oxidative stress in paraventricular nucleus during chronic intermittent hypoxia</a><br/>J Cell Physiol. 2019&emsp;&emsp;PMID:&nbsp;30609027</td><tr/>
<tr><td><strong>052.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/30589940/” target=” blank” rel=”noopener”>AMPA receptors modulate the reorganization of F-actin in Bergmann glia cells through the activation of RhoA</a><br/>J Neurochem. 2019&emsp;&emsp;PMID:&nbsp;30589940</td><tr/>
<tr><td><strong>053.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/31339573/” target=” blank” rel=”noopener”>Inhibition of Notch1 signaling promotes neuronal differentiation and improves functional recovery in spinal cord injury through suppressing the activation of Ras homolog family member A</a><br/>J Neurochem. 2019&emsp;&emsp;PMID:&nbsp;31339573</td><tr/>
<tr><td><strong>054.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824444/” target=”_blank” rel=”noopener”>miR-511-3p protects against cockroach allergen-induced lung inflammation by antagonizing CCL2</a><br/>JCI Insight. 2019&emsp;&emsp;PMID:&nbsp;31536479</td><tr/>
<tr><td><strong>055.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643059″ target=”_blank” rel=”noopener”>Simvastatin pretreatment ameliorates t-PA-induced hemorrhage transformation and MMP-9/TIMP-1 imbalance in thromboembolic cerebral ischemic rats</a><br/>Neuropsychiatr Dis Treat. 2019&emsp;&emsp;PMID:&nbsp;31410004</td><tr/>
<tr><td><strong>056.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884968/” target=” blank” rel=”noopener”>P120-Catenin And Its Phosphorylation On Tyr228 Inhibits Proliferation And Invasion In Colon Adenocarcinoma Cells</a><br/>Onco Targets Ther. 2019&emsp;&emsp;PMID:&nbsp;32063714</td><tr/>
<tr><td><strong>057.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/30846413/” target=”_blank” rel=”noopener”>Increased expression of GEF-H1 promotes colon cancer progression by RhoA signaling</a><br/>Pathology – Research and Practice. 2019&emsp;&emsp;PMID:&nbsp;30846413</td><tr/>
<tr><td><strong>058.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/31028904/” target=”_blank” rel=”noopener”>12(S)-Hydroxyeicosatetraenoic acid downregulates monocyte-derived macrophage efferocytosis: New insights in atherosclerosis</a><br/>Pharmacol Res. 2019&emsp;&emsp;PMID:&nbsp;31028904</td><tr/>
<tr><td><strong>059.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/31321704/” target=” blank” rel=”noopener”>Inhibition of Rac1-dependent forgetting alleviates memory deficits in animal models of Alzheimer’s disease</a><br/>Protein Cell. 2019&emsp;&emsp;PMID:&nbsp;31321704</td><tr/>
<tr><td><strong>060.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416270/” target=”_blank” rel=”noopener”>Profibrotic epithelial phenotype: a central role for MRTF and TAZ</a><br/>Sci Rep. 2019&emsp;&emsp;PMID:&nbsp;30867502</td><tr/>
<tr><td><strong>061.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690958/” target=”_blank” rel=”noopener”>Endothelial RhoA GTPase is essential for in vitro endothelial functions but dispensable for physiological in vivo angiogenesis</a><br/>Scientific Reports. 2019&emsp;&emsp;PMID:&nbsp;31406143</td><tr/>
<tr><td><strong>062.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866437/” target=”_blank” rel=”noopener”>RhoA increases ASIC1a plasma membrane localization and calcium influx in pulmonary arterial smooth muscle cells following chronic hypoxia</a><br/>Am J Physiol Cell Physiol. 2018&emsp;&emsp;PMID:&nbsp;29070491</td><tr/>
<tr><td><strong>063.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260585″ target=”_blank” rel=”noopener”>E3 Ubiquitin-Protein Ligase SMURF1 in the Nucleus Accumbens Mediates Cocaine Seeking</a><br/>Biol Psychiatry. 2018&emsp;&emsp;PMID:&nbsp;30158054</td><tr/>
<tr><td><strong>064.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/29635128/” target=” blank” rel=”noopener”>Naringin attenuates MLC phosphorylation and NF-?B activation to protect sepsis-induced intestinal injury via RhoA/ROCK pathway</a><br/>Biomed Pharmacother. 2018&emsp;&emsp;PMID:&nbsp;29635128</td><tr/>
<tr><td><strong>065.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200100/” target=”_blank” rel=”noopener”>Inhibition of RhoA reduces propofol-mediated growth cone collapse.axonal transport impairment.loss of synaptic connectivity.and behavioural deficits</a><br/>Br J Anaesth. 2018&emsp;&emsp;PMID:&nbsp;29576115</td><tr/>
<tr><td><strong>066.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/29444209/” target=” blank” rel=”noopener”>Geranylgeranyl pyrophosphate synthase facilitates the organization of cardiomyocytes during mid-gestation through modulating protein geranylgeranylation in mouse heart</a><br/>Cardiovasc Res. 2018&emsp;&emsp;PMID:&nbsp;29444209</td><tr/>
<tr><td><strong>067.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924761/” target=”_blank” rel=”noopener”>The Rho GTPase Rnd1 inhibits epithelial–mesenchymal transition in hepatocellular carcinoma and is a favorable anti-metastasis target</a><br/>Cell Death Dis. 2018&emsp;&emsp;PMID:&nbsp;29706627</td><tr/>
<tr><td><strong>068.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/30304669/” target=”_blank” rel=”noopener”>Social Isolation Induces Rac1-Dependent Forgetting of Social Memory</a><br/>Cell Rep. 2018&emsp;&emsp;PMID:&nbsp;30304669</td><tr/>
<tr><td><strong>069.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/30254631/” target=”_blank” rel=”noopener”>Fam65b Phosphorylation Relieves Tonic RhoA Inhibition During T Cell Migration</a><br/>Front Immunol. 2018&emsp;&emsp;PMID:&nbsp;30254631</td><tr/>
<tr><td><strong>070.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028505/” target=”_blank” rel=”noopener”>The Rho regulator Myosin IXb enables nonlymphoid tissue seeding of protective CD8+ T cells</a><br/>J Exp Med. 2018&emsp;&emsp;PMID:&nbsp;29875261</td><tr/>
<tr><td><strong>071.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895035/” target=”_blank” rel=”noopener”>Swedish Nerve Growth Factor Mutation (NGFR100W) Defines a Role for TrkA and p75NTR in Nociception</a><br/>J Neurosci. 2018&emsp;&emsp;PMID:&nbsp;29483280</td><tr/>
<tr><td><strong>072.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/29393423/” target=”_blank” rel=”noopener”>COL1A1 promotes metastasis in colorectal cancer by regulating the WNT/PCP pathway</a><br/>Mol Med Rep. 2018&emsp;&emsp;PMID:&nbsp;29393423</td><tr/>
<tr><td><strong>073.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/29751054/” target=” blank” rel=”noopener”>ß-Elemene Enhances GAP-43 Expression and Neurite Outgrowth by Inhibiting RhoA Kinase Activation in Rats with Spinal Cord Injury</a><br/>Neuroscience. 2018&emsp;&emsp;PMID:&nbsp;29751054</td><tr/>
<tr><td><strong>074.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036455/” target=”_blank” rel=”noopener”>MicroRNA-650 targets inhibitor of growth 4 to promote colorectal cancer progression via mitogen activated protein kinase signaling</a><br/>Oncol Lett. 2018&emsp;&emsp;PMID:&nbsp;30008936</td><tr/>
<tr><td><strong>075.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627671/” target=”_blank” rel=”noopener”>Anti-Inflammatory Activity in Colon Models Is Derived from Δ9-Tetrahydrocannabinolic Acid That Interacts with Additional Compounds in Cannabis Extracts</a><br/> Cannabis Cannabinoid Res. 2017&emsp;&emsp;PMID:&nbsp;29082314</td><tr/>
<tr><td><strong>076.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/28670396/” target=”_blank” rel=”noopener”>Effects of chemerin/CMKLR1 in obesity-induced hypertension and potential mechanism</a><br/>Am J Transl Res. 2017&emsp;&emsp;PMID:&nbsp;28670396</td><tr/>
<tr><td><strong>077.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/28743719/” target=” blank” rel=”noopener”>The atypical receptor CCRL2 is required for CXCR2-dependent neutrophil recruitment and tissue damage</a><br/>Blood. 2017&emsp;&emsp;PMID:&nbsp;28743719</td><tr/>
<tr><td><strong>078.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747023/” target=”_blank” rel=”noopener”>Phoyunnanin E inhibits migration of non-small cell lung cancer cells via suppression of epithelial-to-mesenchymal transition and integrin αv and integrin β3</a><br/>BMC Complement Altern Med. 2017&emsp;&emsp;PMID:&nbsp;29284478</td><tr/>
<tr><td><strong>079.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/28559239/” target=” blank” rel=”noopener”>Escort cells generate a dynamic compartment for germline stem cell differentiation via combined Stat and Erk signalling</a><br/>Development. 2017&emsp;&emsp;PMID:&nbsp;28559239</td><tr/>
<tr><td><strong>080.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/28947533/” target=” blank” rel=”noopener”>Rho differentially regulates the Hippo pathway by modulating the interaction between Amot and Nf2 in the blastocyst</a><br/>Development. 2017&emsp;&emsp;PMID:&nbsp;28947533</td><tr/>
<tr><td><strong>081.&emsp;</strong><a href=””https://pubmed.ncbi.nlm.nih.gov/27836552/”” target=””_blank”” rel=””noopener””>RhoA/ROCK pathway activity is essential for the correct localization of the germ plasm mRNAs in zebrafish embryos</a><br/>Dev Biol. 2017&emsp;&emsp;PMID:&nbsp;27836552</td><tr/>
<tr><td><strong>082.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732150/” target=”_blank” rel=”noopener”>Myosin 1g Contributes to CD44 Adhesion Protein and Lipid Rafts Recycling and Controls CD44 Capping and Cell Migration in B Lymphocytes</a><br/>Front Immunol. 2017&emsp;&emsp;PMID:&nbsp;29321775</td><tr/>
<tr><td><strong>083.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/28887414/” target=”_blank” rel=”noopener”>Progressive polarity loss and luminal collapse disrupt tissue organization in carcinoma</a><br/>Genes Dev. 2017&emsp;&emsp;PMID:&nbsp;28887414</td><tr/>
<tr><td><strong>084.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/29016860/” target=” blank” rel=”noopener”>Primary angle closure glaucoma (PACG) susceptibility gene PLEKHA7 encodes a novel Rac1/Cdc42 GAP that modulates cell migration and blood-aqueous barrier function</a><br/>Hum Mol Genet. 2017&emsp;&emsp;PMID:&nbsp;29016860</td><tr/>
<tr><td><strong>085.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687018/” target=”_blank” rel=”noopener”>The desmoplakin–intermediate filament linkage regulates cell mechanics</a><br/>Mol Biol Cell. 2017&emsp;&emsp;PMID:&nbsp;28495795</td><tr/>
<tr><td><strong>086.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/27830358/” target=” blank” rel=”noopener”>Curcumin inhibits growth of human breast cancer cells through demethylation of DLC1 promoter</a><br/>Mol Cell Biochem. 2017&emsp;&emsp;PMID:&nbsp;27830358</td><tr/>
<tr><td><strong>087.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436224″ target=”_blank” rel=”noopener”>Induction of cell cycle arrest by increasing GTP-RhoA levels via Taxol-induced microtubule polymerization in renal cell carcinoma</a><br/>Mol Med Rep. 2017&emsp;&emsp;PMID:&nbsp;28487984</td><tr/>
<tr><td><strong>088.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/28350093/” target=” blank” rel=”noopener”>Inhibitory effect of Angelica gigas on cold-induced RhoA activation in vascular cells</a><br/>Mol Med Rep. 2017&emsp;&emsp;PMID:&nbsp;28350093</td><tr/>
<tr><td><strong>089.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719012/” target=”_blank” rel=”noopener”>3D microniches reveal the importance of cell size and shape</a><br/>Nat Commun. 2017&emsp;&emsp;PMID:&nbsp;29213086</td><tr/>
<tr><td><strong>090.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/28726800/” target=”_blank” rel=”noopener”>Role of Nicotinamide N-Methyltransferase in Dorsal Striatum in Cocaine Place Preference</a><br/>Neuropsychopharmacology. 2017.&emsp;&emsp;PMID:&nbsp;28726800</td><tr/>
<tr><td><strong>091.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584221/” target=”_blank” rel=”noopener”>EETs reduces LPS-induced hyperpermeability by targeting GRP78 mediated Src activation and subsequent Rho/ROCK signaling pathway</a><br/>Oncotarget. 2017&emsp;&emsp;PMID:&nbsp;28881620</td><tr/>
<tr><td><strong>092.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625153/” target=”_blank” rel=”noopener”>inhibition of RhoA/Rho kinase pathway and smooth muscle contraction by hydrogen sulfide</a><br/>Pharmacol Res Perspect. 2017&emsp;&emsp;PMID:&nbsp;28971603</td><tr/>
<tr><td><strong>093.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224981/” target=”_blank” rel=”noopener”>GGPP-Mediated Protein Geranylgeranylation in Oocyte Is Essential for the Establishment of Oocyte-Granulosa Cell Communication and Primary-Secondary Follicle Transition in Mouse Ovary</a><br/>PLoS Genet. 2017&emsp;&emsp;PMID:&nbsp;28072828</td><tr/>
<tr><td><strong>094.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532275/” target=”_blank” rel=”noopener”>RhoA phosphorylation mediated by Rho/RhoA-associated kinase pathway improves the anti-freezing potentiality of murine hatched and diapaused blastocysts</a><br/>Sci Rep. 2017&emsp;&emsp;PMID:&nbsp;28751650</td><tr/>
<tr><td><strong>095.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/28078487/” target=”_blank” rel=”noopener”>The role of the Nox4-derived ROS-mediated RhoA/Rho kinase pathway in rat hypertension induced by chronic intermittent hypoxia</a><br/>Sleep Breath. 2017&emsp;&emsp;PMID:&nbsp;28078487</td><tr/>
<tr><td><strong>096.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721977/” target=”_blank” rel=”noopener”>Cannabidiol restores intestinal barrier dysfunction and inhibits the apoptotic process induced by Clostridium difficile toxin A in Caco-2 cells</a><br/>United European Gastroenterol J. 2017&emsp;&emsp;PMID:&nbsp;29238589</td><tr/>
<tr><td><strong>097.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/26694899/” target=” blank” rel=”noopener”>Mutations of Cystic Fibrosis Transmembrane Conductance Regulator Gene Cause a Monocyte-Selective Adhesion Deficiency</a><br/>Am J Respir Crit Care Med. 2016&emsp;&emsp;PMID:&nbsp;26694899</td><tr/>
<tr><td><strong>098.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886818″ target=”_blank” rel=”noopener”>Osteoclast-derived microRNA-containing exosomes selectively inhibit osteoblast activity</a><br/>Cell Discov. 2016&emsp;&emsp;PMID:&nbsp;27462462</td><tr/>
<tr><td><strong>099.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/27670698/” target=”_blank” rel=”noopener”>Elongator controls cortical interneuron migration by regulating actomyosin dynamics</a><br/>Cell Res. 2016&emsp;&emsp;PMID:&nbsp;27670698</td><tr/>
<tr><td><strong>100.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/25596714/” target=”_blank” rel=”noopener”>Curcumin inhibits LPA-induced invasion by attenuating RhoA/ROCK/MMPs pathway in MCF7 breast cancer cells</a><br/>Clin Exp Med. 2016&emsp;&emsp;PMID:&nbsp;25596714</td><tr/>
<tr><td><strong>101.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/27188212/” target=” blank” rel=”noopener”>Opposing effects of actin signaling and LFA-1 on establishing the affinity threshold for inducing effector T-cell responses in mice</a><br/>Eur J Immunol. 2016&emsp;&emsp;PMID:&nbsp;27188212</td><tr/>
<tr><td><strong>102.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/27651818/” target=”_blank” rel=”noopener”>Gigantol Inhibits Epithelial to Mesenchymal Process in Human Lung Cancer Cells </a><br/>Evidence-Based Complementary and Alternative Medicine. 2016&emsp;&emsp;PMID:&nbsp;27651818</td><tr/>
<tr><td><strong>103.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919453″ target=”_blank” rel=”noopener”>Thiopurine Prodrugs Mediate Immunosuppressive Effects by Interfering with Rac1 Protein Function</a><br/>J Biol Chem. 2016&emsp;&emsp;PMID:&nbsp;27189938</td><tr/>
<tr><td><strong>104.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/27218883/” target=”_blank” rel=”noopener”>The Semaphorin 4D-RhoA-Akt Signal Cascade Regulates Enamel Matrix Secretion in Coordination with Cell Polarization During Ameloblast Differentiation. </a><br/>J Bone Miner Res. 2016&emsp;&emsp;PMID:&nbsp;27218883</td><tr/>
<tr><td><strong>105.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/27231093/” target=” blank” rel=”noopener”>VEGF-A stimulates podosome-mediated collagen-IV proteolysis in microvascular endothelial cells</a><br/>J Cell Sci. 2016&emsp;&emsp;PMID:&nbsp;27231093</td><tr/>
<tr><td><strong>106.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/27167578/” target=” blank” rel=”noopener”>Alpha 7 nicotinic receptor coupling to heterotrimeric G proteins modulates RhoA activation.cytoskeletal motility.and structural growth</a><br/>J Neurochem. 2016&emsp;&emsp;PMID:&nbsp;27167578</td><tr/>
<tr><td><strong>107.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148245/” target=”_blank” rel=”noopener”>Converging.Synergistic Actions of Multiple Stress Hormones Mediate Enduring Memory Impairments after Acute Simultaneous Stresses</a><br/>J Neurosci. 2016&emsp;&emsp;PMID:&nbsp;27807170</td><tr/>
<tr><td><strong>108.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855537/” target=” blank” rel=”noopener”>RhoA determines lineage fate of mesenchymal stem cells by modulating CTGF-VEGF complex in extracellular matrix</a><br/>Nat Commun. 2016&emsp;&emsp;PMID:&nbsp;27126736</td><tr/>
<tr><td><strong>109.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400263/” target=”_blank” rel=”noopener”>RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics</a><br/>Nature Immunology&#44;2016&emsp;&emsp;PMID:&nbsp;27776107</td><tr/>
<tr><td><strong>110.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125678/” target=”_blank” rel=”noopener”>TGFbeta induces binucleation/polyploidization in hepatocytes through a src-Dependent cytokinesis failure</a><br/>PLoS One. 2016&emsp;&emsp;PMID:&nbsp;27893804</td><tr/>
<tr><td><strong>111.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977536/” target=”_blank” rel=”noopener”>p-Hydroxylcinnamaldehyde induces the differentiation of oesophageal carcinoma cells via the cAMP-RhoA-MAPK signalling pathway</a><br/>Scientific Reports . 2016&emsp;&emsp;PMID:&nbsp;27501997</td><tr/>
<tr><td><strong>112.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/27269634/” target=”_blank” rel=”noopener”>Simulated Microgravity Disrupts Cytoskeleton Organization and Increases Apoptosis of Rat Neural Crest Stem Cells via Upregulating CXCR4 Expression and RhoA-ROCK1-p38 MAPK-p53 Signaling. </a><br/>Stem Cells Dev. 2016&emsp;&emsp;PMID:&nbsp;27269634</td><tr/>
<tr><td><strong>113.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/27396430/” target=”_blank” rel=”noopener”>Expression of G Protein-coupled Receptor 56 Is an Unfavorable Prognostic Factor in Osteosarcoma Patients </a><br/>Tohoku J Exp Med. 2016&emsp;&emsp;PMID:&nbsp;27396430</td><tr/>
<tr><td><strong>114.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473318/” target=” blank” rel=”noopener”>Netrin-1 promotes cell migration and invasion by down-regulation of BVES expression in human hepatocellular carcinoma</a><br/>Am J Cancer Res. 2015&emsp;&emsp;PMID:&nbsp;26101705</td><tr/>
<tr><td><strong>115.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905748/” target=”_blank” rel=”noopener”>Cyclic Mechanical Loading Is Essential for Rac1-Mediated Elongation and Remodeling of the Embryonic Mitral Valve</a><br/>Current Biology. 2015&emsp;&emsp;PMID:&nbsp;26725196</td><tr/>
<tr><td><strong>116.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/26188246/” target=”_blank” rel=”noopener”>Cadherin-11 coordinates cellular migration and extracellular matrix remodeling during aortic valve maturation </a><br/>Dev Biol. 2015&emsp;&emsp;PMID:&nbsp;26188246</td><tr/>
<tr><td><strong>117.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392599/” target=”_blank” rel=”noopener”>Wnt5a and Wnt11 regulate mammalian anterior-posterior axis elongation</a><br/>Development. 2015&emsp;&emsp;PMID:&nbsp;25813538</td><tr/>
<tr><td><strong>118.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/25724163/” target=”_blank” rel=”noopener”>Sodium Ferulate Reduces Portal Pressure Through Inhibition of RhoA/Rho-Kinase and Activation of Endothelial Nitric Oxide Synthase in Cirrhotic Rats</a><br/>Dig Dis Sci. 2015&emsp;&emsp;PMID:&nbsp;25724163</td><tr/>
<tr><td><strong>119.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279736/” target=”_blank” rel=”noopener”>Sphingomyelinase-Like Phosphodiesterase 3b Expression Levels Determine Podocyte Injury Phenotypes in Glomerular Disease</a><br/>J Am Soc Nephrol. 2015&emsp;&emsp;PMID:&nbsp;24925721</td><tr/>
<tr><td><strong>120.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/26290381/” target=” blank” rel=”noopener”>Tetraspanin-3 is an organizer of the multi-subunit Nogo-A signaling complex</a><br/>J Cell Sci. 2015&emsp;&emsp;PMID:&nbsp;26290381</td><tr/>
<tr><td><strong>121.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/26392029/” target=” blank” rel=”noopener”>Dp63RhoGEF regulates auto- and paracrine signaling in cardiac fibroblasts</a><br/>J Mol Cell Cardiol. 2015&emsp;&emsp;PMID:&nbsp;26392029</td><tr/>
<tr><td><strong>122.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/25896910/” target=”_blank” rel=”noopener”>Creutzfeldt-Jakob Disease Subtype-Specific Regional and Temporal Regulation of ADP Ribosylation Factor-1-Dependent Rho/MLC Pathway at Pre-Clinical Stage</a><br/>J Mol Neurosci. 2015&emsp;&emsp;PMID:&nbsp;25896910</td><tr/>
<tr><td><strong>123.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/25783411/” target=”_blank” rel=”noopener”>Kaempferol-3-O-rutinoside from Afgekia mahidoliae promotes keratinocyte migration through FAK and Rac1 activation</a><br/>J Nat Med. 2015&emsp;&emsp;PMID:&nbsp;25783411</td><tr/>
<tr><td><strong>124.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/26109451/” target=”_blank” rel=”noopener”>A bibenzyl from Dendrobium ellipsophyllum inhibits migration in lung cancer cells </a><br/>Journal of Natural Medicines. 2015&emsp;&emsp;PMID:&nbsp;26109451</td><tr/>
<tr><td><strong>125.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510974/” target=” blank” rel=”noopener”>A phosphorylation switch controls the spatiotemporal activation of Rho GTPases in directional cell migration</a><br/>Nat Commun. 2015&emsp;&emsp;PMID:&nbsp;26166433</td><tr/>
<tr><td><strong>126.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/26035691/” target=”_blank” rel=”noopener”>Depletion of histone deacetylase 1 inhibits metastatic abilities of gastric cancer cells by regulating the miR-34a/CD44 pathway</a><br/>Oncology. 2015&emsp;&emsp;PMID:&nbsp;26035691</td><tr/>
<tr><td><strong>127.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/25866159/” target=”_blank” rel=”noopener”>piggyBac Insertional Mutagenesis Screen Identifies a Role for Nuclear RHOA in Human ES Cell Differentiation</a><br/>Stem Cell Reports&#44;2015&emsp;&emsp;PMID:&nbsp;25866159</td><tr/>
<tr><td><strong>128.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/25503138/” target=”_blank” rel=”noopener”>Cisplatin at Sub-toxic Levels Mediates Integrin Switch in Lung Cancer Cells</a><br/>Anticancer Research. 2014&emsp;&emsp;PMID:&nbsp;25503138</td><tr/>
<tr><td><strong>129.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/24447566/” target=”_blank” rel=”noopener”>Syndecan-2 regulation of morphology in breast carcinoma cells is dependent on RhoGTPases</a><br/>Biochimica et Biophysica Acta (BBA) – General Subjects. 2014&emsp;&emsp;PMID:&nbsp;24447566</td><tr/>
<tr><td><strong>130.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/24902944/” target=” blank” rel=”noopener”>The glucocorticoid dexamethasone inhibits U937 cell adhesion and neutrophil release via RhoA/ROCK1-dependent and independent pathways</a><br/>Cell Physiol Biochem. 2014&emsp;&emsp;PMID:&nbsp;24902944</td><tr/>
<tr><td><strong>131.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/25022961/” target=”_blank” rel=”noopener”>MIF inhibits monocytic movement through a non-canonical receptor and disruption of temporal Rho GTPase activities in U-937 cells</a><br/>Cytokine. 2014&emsp;&emsp;PMID:&nbsp;25022961</td><tr/>
<tr><td><strong>132.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900538/” target=”_blank” rel=”noopener”>Podocyte-specific GLUT4 deficient mice have fewer and larger podocytes and are protected from diabetic nephropathy</a><br/>Diabetes. 2014&emsp;&emsp;PMID:&nbsp;24101677</td><tr/>
<tr><td><strong>133.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/24972930/” target=” blank” rel=”noopener”>ARGS5 promotes arterial growth during arteriogenesis</a><br/>EMBO Mol Med. 2014&emsp;&emsp;PMID:&nbsp;24972930</td><tr/>
<tr><td><strong>134.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154134/” target=”_blank” rel=”noopener”>RGS5 promotes arterial growth during arteriogenesis</a><br/>EMBO Mol Med. 2014&emsp;&emsp;PMID:&nbsp;24972930</td><tr/>
<tr><td><strong>135.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/24859471/” target=” blank” rel=”noopener”>Loss of ARHGDIA expression is associated with poor prognosis in HCC and promotes invasion and metastasis of HCC cells</a><br/>Int J Oncol. 2014&emsp;&emsp;PMID:&nbsp;24859471</td><tr/>
<tr><td><strong>136.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/24463819/” target=”_blank” rel=”noopener”>Epithelial repair is a two-stage process driven first by dying cells and then by their neighbours</a><br/>J Cell Sci. 2014&emsp;&emsp;PMID:&nbsp;24463819</td><tr/>
<tr><td><strong>137.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/24610943/” target=” blank” rel=”noopener”>Maintenance of stereocilia and apical junctional complexes by Cdc42 in cochlear hair cells</a><br/>J Cell Sci. 2014&emsp;&emsp;PMID:&nbsp;24610943</td><tr/>
<tr><td><strong>138.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/25329306/” target=”_blank” rel=”noopener”>Triclosan Potentiates Epithelial-To-Mesenchymal Transition in Anoikis-Resistant Human Lung Cancer Cells</a><br/>PLoS One. 2014&emsp;&emsp;PMID:&nbsp;25329306</td><tr/>
<tr><td><strong>139.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/23645207/” target=”_blank” rel=”noopener”>Foxc2 induces Wnt4 and Bmp4 expression during muscle regeneration and osteogenesis</a><br/>Cell Death and Differentiation. 2013&emsp;&emsp;PMID:&nbsp;23645207</td><tr/>
<tr><td><strong>140.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824649/” target=”_blank” rel=”noopener”>Loss of TAK1 increases cell traction force in a ROS-dependent manner to drive epithelial–mesenchymal transition of cancer cells</a><br/>Cell Death and Disease&#44;2013&emsp;&emsp;PMID:&nbsp;24113182</td><tr/>
<tr><td><strong>141.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/23550588/” target=”_blank” rel=”noopener”>Transgenesis of the Wolffian duct visualizes dynamic behavior of cells undergoing tubulogenesis in vivo</a><br/>Dev Growth Differ. 2013&emsp;&emsp;PMID:&nbsp;23550588</td><tr/>
<tr><td><strong>142.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806621/” target=”_blank” rel=”noopener”>Cyclodextrin protects podocytes in diabetic kidney disease</a><br/>Diabetes. 2013&emsp;&emsp;PMID:&nbsp;23835338</td><tr/>
<tr><td><strong>143.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711289/” target=”_blank” rel=”noopener”>N-glycosylation induces collagen triple helix repeat containing 1 (CTHRC1) and drives oral cancer cell migration</a><br/>J Biol Chem. 2013&emsp;&emsp;PMID:&nbsp;23703614</td><tr/>
<tr><td><strong>144.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/24368807/” target=” blank” rel=”noopener”>JAK tyrosine kinases promote hierarchical activation of Rho and Rap modules of integrin activation</a><br/>J Cell Biol. 2013&emsp;&emsp;PMID:&nbsp;24368807</td><tr/>
<tr><td><strong>145.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/23895422/” target=” blank” rel=”noopener”>Amyloid beta₁₋₄₂ (Aβ₄₂) up-regulates the expression of sortilin via the p75(NTR)/RhoA signaling pathway</a><br/>J Neurochem. 2013&emsp;&emsp;PMID:&nbsp;23895422</td><tr/>
<tr><td><strong>146.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716611/” target=” blank” rel=”noopener”>MMP-9 and CXCL8/IL-8 Are Potential Therapeutic Targets in Epidermolysis Bullosa Simplex</a><br/>PLoS One. 2013&emsp;&emsp;PMID:&nbsp;23894602</td><tr/>
<tr><td><strong>147.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/22505643/” target=”_blank” rel=”noopener”>Sustained therapeutic hypercapnia attenuates pulmonary arterial Rho-kinase activity and ameliorates chronic hypoxic pulmonary hypertension in juvenile rats</a><br/>Am J Physiol Heart Circ Physiol. 2012&emsp;&emsp;PMID:&nbsp;22505643</td><tr/>
<tr><td><strong>148.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/21900451/” target=”_blank” rel=”noopener”>WT1-interacting protein (Wtip) regulates podocyte phenotype by cell-cell and cell-matrix contact reorganization</a><br/>Am J Physiol Renal Physiol. 2012&emsp;&emsp;PMID:&nbsp;21900451</td><tr/>
<tr><td><strong>149.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/22717125/” target=”_blank” rel=”noopener”>Invadopodia and rolling-type motility are specific features of highly invasive p190(bcr-abl) leukemic cells</a><br/>Eur J Cell Biol. 2012&emsp;&emsp;PMID:&nbsp;22717125</td><tr/>
<tr><td><strong>150.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/22514275/” target=”_blank” rel=”noopener”>LINGO-1.a transmembrane signaling protein.inhibits oligodendrocyte differentiation and myelination through intercellular self-interactions</a><br/>J Biol Chem. 2012&emsp;&emsp;PMID:&nbsp;22514275</td><tr/>
<tr><td><strong>151.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/22923615/” target=”_blank” rel=”noopener”>Olfactomedin 1 interacts with the Nogo A receptor complex to regulate axon growth</a><br/>J Biol Chem. 2012&emsp;&emsp;PMID:&nbsp;22923615</td><tr/>
<tr><td><strong>152.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/22573889/” target=”_blank” rel=”noopener”>A role for myosin IXb.a motor-RhoGAP chimera.in epithelial wound healing and tight junction regulation</a><br/>Mol Biol Cell. 2012&emsp;&emsp;PMID:&nbsp;22573889</td><tr/>
<tr><td><strong>153.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/22983395/” target=” blank” rel=”noopener”>Endothelial PI3K-C2à.a class II PI3K.has an essential role in angiogenesis and vascular barrier function</a><br/>Nat Med. 2012&emsp;&emsp;PMID:&nbsp;22983395</td><tr/>
<tr><td><strong>154.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271155″ target=”_blank” rel=”noopener”>C3 Peptide Promotes Axonal Regeneration and Functional Motor Recovery after Peripheral Nerve Injury</a><br/>Neurotherapeutics. 2012&emsp;&emsp;PMID:&nbsp;21866396</td><tr/>
<tr><td><strong>155.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/22139079/” target=”_blank” rel=”noopener”>The transcriptional coactivators megakaryoblastic leukemia 1/2 mediate the effects of loss of the tumor suppressor deleted in liver cancer 1</a><br/>Oncogene. 2012&emsp;&emsp;PMID:&nbsp;22139079</td><tr/>
<tr><td><strong>156.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338794″ target=”_blank” rel=”noopener”>ProBDNF Collapses Neurite Outgrowth of Primary Neurons by Activating RhoA</a><br/>PLoS One. 2012&emsp;&emsp;PMID:&nbsp;22558255</td><tr/>
<tr><td><strong>157.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277110″ target=”_blank” rel=”noopener”>Differential regulation of the activity of deleted in liver cancer 1 (DLC1) by tensins controls cell migration and transformation</a><br/>Proc Natl Acad Sci U S A. 2012&emsp;&emsp;PMID:&nbsp;22307599</td><tr/>
<tr><td><strong>158.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/21036919/” target=”_blank” rel=”noopener”>Polarized migration of lymphatic endothelial cells is critically dependent on podoplanin regulation of Cdc42</a><br/>Am J Physiol Lung Cell Mol Physiol. 2011&emsp;&emsp;PMID:&nbsp;21036919</td><tr/>
<tr><td><strong>159.&emsp;</strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062424″ target=”_blank” rel=”noopener”>Asymmetric Mbc.active Rac1 and F-actin foci in the fusion-competent myoblasts during myoblast fusion in Drosophila</a><br/>Development. 2011&emsp;&emsp;PMID:&nbsp;21389053</td><tr/>
<tr><td><strong>160.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/21985251/” target=”_blank” rel=”noopener”>Ethanol increases p190RhoGAP activity.leading to actin cytoskeleton rearrangements</a><br/>J Neurochem. 2011&emsp;&emsp;PMID:&nbsp;21985251</td><tr/>
<tr><td><strong>161.&emsp;</strong><a href=”https://pubmed.ncbi.nlm.nih.gov/20478922/” target=”_blank” rel=”noopener”>G(alpha)12/13 inhibition enhances the anticancer effect of bortezomib through PSMB5 downregulation</a><br/>Carcinogenesis. 2010&emsp;&emsp;PMID:&nbsp;20478922</td><tr/>
</tbody>
</table>