武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

微信:Neweast Biosciences

咨询:027 – 63497286 

Human IL18 Protein, mFc Tag

Recombinant Human IL18 with C-terminal mouse Fc tag
5/5

¥479.00

货号:11358

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11358
产品全名:   人 IL18 蛋白
规格:   10/50/100 µg
基因符号   IGIF;IL-1g;IL-18;IL1F4
目标蛋白:    IL18
UNIPROT ID:    Q14116
描述:   Recombinant Human IL18 with C-terminal mouse Fc tag
背景:     The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2020]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 44.3 kDa after removal of the signal peptide.The apparent molecular mass of IL18-mFc is approximately 35-55 kDa due to glycosylation.
分子特征:   IL18(Thr37-Asp197) mFc(Pro99-Lys330)
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human IL18 Protein, mFc Tag on SDS-PAGE under reducing condition.
           引用文献