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Human IFNAR1 Protein, mFc Tag

Recombinant human IFNAR1 Protein with C-terminal Mouse Fc tag
5/5

$659.00

货号:11526

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11526
产品全名:   人 IFNAR1 蛋白
规格:   10/50/100 µg
基因符号   Interferon alpha/beta receptor 1;FN-R-1;FN-alpha/beta receptor 1;RF2-1;ype I interferon receptor 1
目标蛋白:    IFNAR1
UNIPROT ID:    P17181
描述:   Recombinant human IFNAR1 Protein with C-terminal Mouse Fc tag
背景:     The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor. [provided by RefSeq, Jul 2020]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 73 kDa after removal of the signal peptide. The apparent molecular mass of IFNAR1-mFc is approximately 100-130 kDa due to glycosylation.
分子特征:   IFNAR1(Lys28-Lys436) mFc(Pro99-Lys330)
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human IFNAR1 Protein, mFc Tag on SDS-PAGE under reducing condition.

Figure 2. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human IFNAR1 Protein, mFc Tag (11526) can bind Anti-IFNAR1 Neutralizing antibody 28115 in a linear range of 1.22-312.50 ng/mL.
           引用文献