武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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Human CD130 Protein, hFc Tag

Recombinant human CD130 protein with C-terminal human Fc tag
5/5

$415.00

货号:11595

规格: 100 μg

库存状态:Under development

           产品描述          
货号:   11595
产品全名:   人 CD130 蛋白
规格:   10/50/100 µg
基因符号   CD130;CDW130;GP130;IL-6RB
目标蛋白:    CD130
UNIPROT ID:    P40189
描述:   Recombinant human CD130 protein with C-terminal human Fc tag
背景:     The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 91.19 kDa after removal of the signal peptide.
分子特征:   CD130(Glu23-Glu619) hFc(Glu99-Ala330)
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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