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Human CCR7 Protein, hFc Tag

Recombinant Human CCR7 with C-terminal human Fc tag
5/5

$445.00

货号:11606

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11606
产品全名:   人 CCR7 蛋白
规格:   10/50/100 µg
基因符号   BLR2;CC-CKR-7;CCR-7;CD197;CDw197;CMKBR7;EBI1
目标蛋白:    CCR7
UNIPROT ID:    P32248
描述:   Recombinant Human CCR7 with C-terminal human Fc tag
背景:     The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 30.2 kDa after removal of the signal peptide. The apparent molecular mass of CCR7-hFc is approximately 35-55 kDa due to glycosylation.
分子特征:   CCR7(Glu25-Trp59) hFc(Glu99-Ala330)
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human CCR7 Protein, hFc Tag on SDS-PAGE under reducing condition.
           引用文献