武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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ERBB2(D769Y)

Anti-ERBB2(D769Y) Mouse Monoclonal Antibody
5/5

$4,800.00

货号:26382

规格: 100 微升

库存状态:In Stock

           产品描述          
产品名称:   ERBB2(D769Y) 小鼠单抗
货号:   26382
基因符号:   ERBB2/HER2/Neu/c-Neu
描述:   ERBB2(D769Y) 小鼠单抗
背景:   The HER-2/neu oncogene, a member of the epidermal growth factor receptor or erb-B gene-like family, encodes a transmembrane tyrosine kinase receptor that mediates extracellular signals activated by epidermal growth factors. Her2 abnormal has been strongly associated with many malignant tumors, especially with breast cancers. The expression level of Her2 is an important criteria in clinic evaluating of the progression of breast cancer.
免疫原:   A synthetic peptide from the internal region of ERBB2 which includes the mutation of D769Y, human origin.
经过测试的应用:   ELISA, IF, IHC
推荐稀释比:   ELISA: 1:1000-1:2000IF: 1:500-1:1000IHC: 1:50-1:100
Concentration:   1 mg/ml
种属反应性:   Mouse
形式:   Liquid
克隆性:   Monoclonal
亚型:   IgG
纯化:   Purified from ascites
成分:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
种属反应性:  Recognizes D769Y mutant, but not wild type ERBB2 of vertebrates.
储存条件:    Store at -20°C. Avoid repeated freezing and thawing
Immunofluorescence:  Immunofluorescence of cells expressing ERBB2 proteins with Anti-ERBB2(D769Y) antibody.HEK293T cells were transfected with pCDNA3-GFP-ERBB2(D769Y) plasmid, pCDNA3-GFP-ERBB2 (WT) plasmid or pCDNA3-GFP-ERBB2 (D769H) plasmid, then fixed and stained with Anti-ERBB2(D769Y) monoclonal antibody (货号:26382).
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