武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

微信:Neweast Biosciences

咨询:027 – 63497286 

Human BACE1 Protein, His Tag

Recombinant Human BACE1 Protein with C-terminal 6XHis tag
5/5

¥415.00

货号:11873

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11873
产品全名:   人 BACE1 蛋白
规格:   10/50/100 µg
基因符号   ASP2;BACE;HSPC104
目标蛋白:    BACE1
UNIPROT ID:    P56817
描述:   Recombinant Human BACE1 Protein with C-terminal 6xHis tag
背景:     This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. [provided by RefSeq, Nov 2015]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 49.3 kDa after removal of the signal peptide. The apparent molecular mass of BACE1-His is approximately 55-100 kDa due to glycosylation.
分子特征:   BACE1(Thr22-Thr457) 6×His tag
纯化:   The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human BACE1 Protein, His Tag on SDS-PAGE under reducing condition.
           引用文献