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TNFRSF10B (DM114) Rabbit mAb

Anti-TNFRSF10B (DM114) Rabbit Monoclonal Antibody
5/5

¥445.00

货号:28459

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   28459
产品全名:   TNFRSF10B(DM114) 兔单克隆抗体
基因符号   TNFRSF10B;TRAILR2;TRAIL-R2;CD262;DR5;KILLER;TRICK2;ZTNFR9;TRICKB
描述:   TNFRSF10B antibody(DM114) 兔单克隆抗体
背景:   The protein encoded by this gene is a member of the TNF-receptor superfamily; and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10:TRAIL:APO-2L); and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD; a death domain containing adaptor protein; is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
经过测试的应用:   ELISA; Flow Cyt
推荐稀释比:   ELISA 1:5000-10000; Flow Cyt 1:100
种属反应性:   Rabbit
亚型:   Rabbit IgG
纯化:   Purified from cell culture supernatant by affinity chromatography
种属反应性:   人 TNFRSF10B
成分:   Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human TNFRSF10B protein, mFc tagged protein 11277 can bind Rabbit anti-TNFRSF10B monoclonal antibody  (clone: DM114) in a linear range of 0.6-90 ng/ml.

Figure 2. TNFRSF10B protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with Anti-TNFRSF10B  (DM114) on Expi293 cells transfected with human TNFRSF10B(Blue histogram) or Expi293 transfected with irrelevant protein(Red histogram), and  Isotype antibody on Expi293 transfected with irrelevant protein(Orange histogram).
           引用文献