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Human TLR9 Full Length Protein

Human TLR9 Full Length Protein-Synthetic Nanodisc
5/5

¥30,000.00

货号:11127

规格: 50 μg

库存状态:In Stock

           产品描述          
货号:   11127
产品全名:   人 TLR9 Full Length 蛋白
规格:   10/50/100 µg
基因符号   CD289
目标蛋白:    TLR9
UNIPROT ID:    Q9NR96
描述:   人 TLR9 full length protein-synthetic nanodisc
背景:     The protein is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
物种/宿主:    HEK293
分子量:   The human full length TLR9 protein has a MW of 115.9 kDa
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure1. Elisa plates were pre-coated with Flag Tag TLR9-Nanodisc (0.2 µg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with TLR9-Nanodisc is 2.467ng/ml.

Figure2. Human TLR9-Nanodisc, Flag Tag on SDS-PAGE
           引用文献