武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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TIM3 (DM83) Rabbit mAb

Anti-TIM3 (DM83) Rabbit Monoclonal Antibody
5/5

¥445.00

货号:28407

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   28407
产品全名:   TIM3(DM83) 兔单克隆抗体
基因符号   HAVCR2; TIM3; TIMD3; FLJ14428; KIM3
描述:   TIM3 antibody(DM83) 兔单克隆抗体
背景:   The protein encoded by this gene belongs to the immunoglobulin superfamily; and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions; whereas; Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation; and inhibits Th1-mediated auto- and alloimmune responses; and promotes immunological tolerance.
经过测试的应用:   ELISA; Flow Cyt
推荐稀释比:   ELISA 1:5000-10000; Flow Cyt 1:100
种属反应性:   Rabbit
亚型:   Rabbit IgG
纯化:   Purified from cell culture supernatant by affinity chromatography
种属反应性:   人 TIM3
成分:   Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human TIM3 protein, mFc-His tagged protein 11158 can bind Rabbit anti-TIM3 monoclonal antibody ( clone: DM83) in a linear range of 0.32-40 ng/ml.

Figure 2. Expi 293 cell line transfected with irrelevant protein  (A) and human TIM3  (B) were surface stained with Rabbit anti-TIM3 monoclonal antibody 1µg/ml ( clone: DM83) followed by Alexa 488-conjugated anti-rabbit IgG secondary antibody.
           引用文献