武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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RET(C634Y)

Anti-RET(C634Y) Mouse Monoclonal Antibody
5/5

$4,800.00

货号:26146

规格: 100 微升

库存状态:In Stock

           产品描述          
产品名称:   RET(C634Y) 小鼠单抗
货号:   26146
基因符号:   RET, PTC, CDHF12, CAHF16, HSCR1, MEN2A, MEN2B
描述:   RET(C634Y) 小鼠单抗
背景:   RET protein is encoded by the RET proto- oncogene. It is a receptor tyrosine kinase. RET loss of function mutations are associated with the development of Hirschsprung’s disease, while gain of function mutations are associated with development of various types of human cancer, including medullary thyroid carcinoma, multiple endocrine neoplasia type 2A and 2B, pheochromocytoma and parathyroid hyperplasia.
免疫原:   A synthetic peptide from the internal region of RET which includes the mutation of C634Y, human origin.
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   ELISA: 1:1000-1:2000WB: 1:500-1:1000IHC: 1:50-1:100
Concentration:   0.5 mg/ml
种属反应性:   Mouse
形式:   Liquid
克隆性:   Monoclonal
亚型:   IgG
纯化:   Purified from ascites
成分:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
种属反应性:  Recognizes C634Y mutant, but not wild type RET of vertebrates.
储存条件:    Store at -20°C. Avoid repeated freezing and thawing
蛋白质印迹:  Western blot analysis of recombinant RET(C634Y) and wild type proteins. Purified His-tagged RET(C634Y) protein (lane1) and corresponding wild type protein (lane2) were blotted with Anti-RET(C634Y) monoclonal antibody (货号:26146).
免疫沉淀/蛋白质印迹:  Immunofluorescence of cells expressing RET proteins with Anti-RET(C634Y) antibody. HEK293T cells were transfected with pCDNA3-GFP-RET (WT) plasmid (left column) or pCDNA3-GFP-RET(C634Y) plasmid (right column), then fixed and stained with Anti-RET(C634Y) monoclonal antibody (货号:26146).
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