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Mouse PD-1 Protein, hFc Tag

Recombinant mouse PD-1 protein with C-terminal human Fc tag
5/5

¥389.00

货号:12221

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   12221
产品全名:   Mouse PD-1 蛋白
规格:   10/50/100 µg
基因符号   Pdcd1;Pdc1;Ly101
目标蛋白:    PD-1
UNIPROT ID:    Q02242
描述:   Recombinant mouse PD-1 protein with C-terminal human Fc tag
背景:     Involved in negative regulation of immune response. Acts upstream of or within negative regulation of apoptotic process; negative regulation of tolerance induction; and positive regulation of apoptotic process. Located in external side of plasma membrane. Is expressed in retina. Used to study dilated cardiomyopathy and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in autoimmune disease (multiple); hepatitis B; hepatitis C; hepatocellular carcinoma; and lupus nephritis. Orthologous to human PDCD1 (programmed cell death 1). [provided by Alliance of Genome Resources, Apr 2022]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 42.3 kDa after removal of the signal peptide. The apparent molecular mass of mPD-1-hFc is approximately 35-70 kDa due to glycosylation.
分子特征:   Mouse PD-1(Leu25-Gln167) hFc(Glu99-Ala330)
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Mouse PD-1 Protein, hFc Tag on SDS-PAGE under reducing condition.
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