| 货号: 12223 |
| 产品全名: Mouse IGF-1R 蛋白 |
| 规格: 10/50/100 µg |
| 基因符号 hyft;CD221;IGF1R |
| 目标蛋白: IGF-1R |
| UNIPROT ID: Q60751 |
| 描述: Recombinant mouse IGF-1R protein with C-terminal 6xHis tag |
| 背景: Enables insulin-like growth factor binding activity. Involved in several processes, including adrenal gland development; positive regulation of cold-induced thermogenesis; and positive regulation of meiotic cell cycle. Acts upstream of or within several processes, including gland development; peptidyl-tyrosine autophosphorylation; and regulation of intracellular signal transduction. Located in T-tubule. Is integral component of membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; limb; and lung. Human ortholog(s) of this gene implicated in several diseases, including dementia (multiple); kidney cancer (multiple); liver disease (multiple); nervous system cancer (multiple); and neurodegenerative disease (multiple). Orthologous to human IGF1R (insulin like growth factor 1 receptor). [provided by Alliance of Genome Resources, Apr 2022] |
| 物种/宿主: HEK293 |
| 分子量: The protein has a predicted molecular mass of 104.5 kDa after removal of the signal peptide. |
| 分子特征: Mouse IGF-1R(Glu31-His936) 6×His tag |
| 纯化: The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| 储存和运输: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Mouse IGF-1R Protein, His Tag on SDS-PAGE under reducing condition. |
