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Mouse DNAM-1 Protein, hFc Tag

Recombinant mouse DNAM-1 protein with C-terminal human Fc tag
5/5

¥550.00

货号:12165

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   12165
产品全名:   Mouse DNAM-1 蛋白
规格:   10/50/100 µg
基因符号   CD226;PTA1
目标蛋白:    DNAM-1
UNIPROT ID:    Q5DW69
描述:   Recombinant mouse DNAM-1 protein with C-terminal human Fc tag
背景:     Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding.[UniProtKB/Swiss-Prot Function]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 52.9 kDa after removal of the signal peptide. The apparent molecular mass of mDNAM-1-hFc is approximately 55-70 kDa due to glycosylation.
分子特征:   Mouse DNAM-1(Glu19-Pro254) hFc(Glu99-Ala330)
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Mouse DNAM1 Protein, hFc Tag on SDS-PAGE under reducing condition.
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