武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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JAK2(R683G)

Anti-JAK2(R683G) Mouse Monoclonal Antibody
5/5

$4,800.00

货号:26314

规格: 100 微升

库存状态:In Stock

           产品描述          
产品名称:   JAK2(R683G) 小鼠单抗
货号:   26314
规格:   100 µL
基因符号:   JAK2, JTK10, THCYT3
描述:   JAK2(R683G) 小鼠单抗
背景:    JAK2 is a non-receptor tyrosine kinase. It is a number of the Janus kinase family and has been implicated in signaling by members of the type II cytokine receptor family, the GM-CSF receptor family, the gp130 receptor family, and the single chain receptors. JAK2 orthologs have been identified in all mammals for which complete genome genome data are available. Mutations of JAK2 have been implicated in polycythemia vera, essential thrombocythemia, and myelofibrosis as well as other myeloproliferative disorders.
免疫原:   A synthetic peptide from the internal region of JAK2 which includes the mutation of R683G, human origin.
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   ELISA: 1:1000-1:2000WB: 1:500-1:1000IHC: 1:50-1:100
Concentration:   0.5 mg/ml
种属反应性:   Mouse
形式:   Liquid
克隆性:   Monoclonal
亚型:   IgG
纯化:   Purified from ascites
Preservative:  No
成分:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
种属反应性:  Recognizes R683G mutant, but not wild type JAK2 of vertebrates.
储存条件:    Store at -20°C. Avoid repeated freezing and thawing
蛋白质印迹:  Western blot analysis of recombinant JAK2(R683G) and wild type proteins.Purified His-tagged JAK2(R683G) protein (lane2) and corresponding wild type protein (lane1) were blotted with Anti-JAK2(R683G) monoclonal antibody (货号:26314).
Immunofluorescence:  Immunofluorescence of cells expressing JAK2 proteins with Anti-JAK2(R683G) antibody.HEK293T cells were transfected with pCDNA3-GFP-JAK2(R683G) plasmid, pCDNA3-GFP-JAK2 (WT) plasmid, pCDNA3-GFP-JAK2 (R683S) plasmid or pCDNA3-GFP-JAK2 (R683T) plasmid, then fixed and stained with Anti-JAK2(R683G) monoclonal antibody (货号:26314).
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