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IL4RA (DMC284) IgG1 Chimeric mAb

Anti-IL4RA (DMC284) IgG1 Chimeric Monoclonal Antibody
5/5

¥445.00

货号:28192

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   28192
产品全名:   IL4RA(DMC284) IgG1 Chimeric 单抗
基因符号   CD124; IL-4RA; IL4RA
描述:   IL4RA antibody(DMC284) IgG1 Chimeric 单抗
背景:   This gene encodes the alpha chain of the interleukin-4 receptor; a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein; and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy; a condition that can manifest itself as allergic rhinitis; sinusitus; asthma; or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.
经过测试的应用:   Flow Cyt
推荐稀释比:   Flow Cyt 1:100
种属反应性:   Rabbit
亚型:   Rabbit:Human Fc chimeric IgG1
纯化:   Purified from cell culture supernatant by affinity chromatography
种属反应性:   人 IL4RA
成分:   Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-IL4RA (DMC284) on Expi293 cells transfected with human IL4RA (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
           引用文献