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Human TMEM173 Protein, hFc Tag

Recombinant human TMEM173 protein with N-terminal Human Fc tag
5/5

$479.00

货号:11342

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11342
产品全名:   人 TMEM173 蛋白
规格:   10/50/100 µg
基因符号   ERIS;hMITA;hSTING;MITA;MPYS;NET23;SAVI;STING;STING-beta;TMEM173
目标蛋白:    TMEM173
UNIPROT ID:    Q86WV6
描述:   Recombinant human TMEM173 protein with N-terminal Human Fc tag
背景:     This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 53.2 kDa after removal of the signal peptide.
分子特征:   hFc(Glu99-Ala330) TMEM173 (Leu139-Ser379)
纯化:   The purity of the protein is greater than 90% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human TMEM173 Protein, hFc Tag on SDS-PAGE under reducing condition.
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