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Human RSPO1(21-263) Protein, His Tag

Recombinant human RSPO1(21-263) protein with C-terminal 6XHis tag
5/5

$659.00

货号:11567

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11567
产品全名:   人 RSPO1(21-263) 蛋白
规格:   10/50/100 µg
基因符号   R-spondin-1;hRspo1
目标蛋白:    RSPO1
UNIPROT ID:    Q2MKA7
描述:   Recombinant human RSPO1(21-263) protein with C-terminal 6xHis tag
背景:     This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 27.6 kDa after removal of the signal peptide. The apparent molecular mass of RSPO1(21-263)-His is approximately 35-55 kDa due to glycosylation.
分子特征:   RSPO1(21-263)(Ser21-Ala263) 6×His tag
纯化:   The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human RSPO1(21-263) Protein, His Tag on SDS-PAGE under reducing condition.
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