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Human ROR1 (312-391) Protein, hFc Tag

Recombinant Human ROR1(312-391) Protein with N-terminal human Fc tag
5/5

¥389.00

货号:11426

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11426
产品全名:   人 ROR1 (312-391) 蛋白
规格:   10/50/100 µg
基因符号   ROR1;TRKR1
目标蛋白:    ROR1
UNIPROT ID:    Q01973
描述:   Recombinant Human ROR1(312-391) Protein with N-terminal human Fc tag
背景:     This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 35.2 kDa after removal of the signal peptide.The apparent molecular mass of hFc- ROR1(312-391) is approximately 35-55 kDa due to glycosylation.
分子特征:   hFc(Glu99-Ala330) ROR1(Lys312-Cys391)
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human ROR1(312-391) Protein, hFc Tag on SDS-PAGE under reducing condition.
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