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Human PLAT Protein, His Tag

Recombinant Human PLAT Protein with C-terminal 6XHis tag
5/5

¥389.00

货号:11972

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11972
产品全名:   人 PLAT 蛋白
规格:   10/50/100 µg
基因符号   T-PA;TPA
目标蛋白:    PLAT
UNIPROT ID:    P00750
描述:   Recombinant Human PLAT Protein with C-terminal 6xHis tag
背景:     This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 59.9 kDa after removal of the signal peptide. The apparent molecular mass of PLAT-His is approximately 55-70 kDa due to glycosylation.
分子特征:   PLAT(Ser36-Pro562) 6×His tag
纯化:   The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1.Human PLAT Protein, His Tag on SDS-PAGE under reducing condition.
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