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Human NTRK1 Protein, hFc Tag

Recombinant Human NTRK1 Protein with C-terminal human Fc tag
5/5

$389.00

货号:11371

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11371
产品全名:   人 NTRK1 蛋白
规格:   10/50/100 µg
基因符号   MTC;p140-TrkA;TRK;Trk-A;TRK1;TRKA
目标蛋白:    NTRK1
UNIPROT ID:    P04629
描述:   Recombinant Human NTRK1 Protein with C-terminal human Fc tag
背景:     This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 67.4 kDa after removal of the signal peptide.The apparent molecular mass of NTRK1-hFc is approximately 70-130 kDa due to glycosylation.
分子特征:   NTRK1(Ala33-Phe410) hFc(Glu99-Ala330)
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human NTRK1 Protein, hFc Tag on SDS-PAGE under reducing condition.
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