武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

微信:Neweast Biosciences

咨询:027 – 63497286 

Human NEFL Protein, hFc Tag

Recombinant Human NEFL with C-terminal human Fc tag
5/5

$479.00

货号:11455

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11455
产品全名:   人 NEFL 蛋白
规格:   10/50/100 µg
基因符号   CMT1F;CMT2E;CMTDIG;NF-L;NF68;NFL;PPP1R110
目标蛋白:    NEFL
UNIPROT ID:    P07196
描述:   Recombinant Human NEFL with C-terminal human Fc tag
背景:     Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 87.5 kDa after removal of the signal peptide. The apparent molecular mass of NEFL-hFc is approximately 35-55 kDa due to glycosylation.
分子特征:   NEFL(Ser2-Asp543) hFc(Glu99-Ala330)
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human NEFL Protein, hFc Tag on SDS-PAGE under reducing condition.
           引用文献