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Human MUC18 Protein, His Tag

Recombinant human MUC18 protein with C-terminal 6XHis tag
5/5

$389.00

货号:11524

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11524
产品全名:   人 MUC18 蛋白
规格:   10/50/100 µg
基因符号   Cell surface glycoprotein MUC18;ell surface glycoprotein P1H12;elanoma cell adhesion molecule;elanoma-associated antigen A32;elanoma-associated antigen MUC18;-endo 1 endothelial-associated antigen;D146
目标蛋白:    MUC18
UNIPROT ID:    P43121
描述:   Recombinant human MUC18 protein with C-terminal 6xHis tag
背景:     Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.[UniProtKB/Swiss-Prot Function]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 60.6 kDa after removal of the signal peptide. The apparent molecular mass of MUC18-His is approximately 70-100 kDa due to glycosylation.
分子特征:   MUC18(Val24-Gly559) 6×His tag
纯化:   The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human MUC18  Protein, His Tag on SDS-PAGE under reducing condition.
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