| 货号: 11536 |
| 产品全名: 人 IL1R2 蛋白 |
| 规格: 10/50/100 µg |
| 基因符号 IL-1RT2;IL1RB;CDw121b;IL-1R-beta;CD121b |
| 目标蛋白: IL1R2 |
| UNIPROT ID: P27930 |
| 描述: Recombinant human IL1R2 protein with C-terminal 6xHis tag |
| 背景: The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. [provided by RefSeq, May 2012] |
| 物种/宿主: HEK293 |
| 分子量: The protein has a predicted molecular mass of 38.6 kDa after removal of the signal peptide. The apparent molecular mass of IL1R2-His is approximately 35-55 kDa due to glycosylation. |
| 分子特征: IL1R2(Phe14-Glu343) 6×His tag |
| 纯化: The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| 储存和运输: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Human IL1R2 Protein, His Tag on SDS-PAGE under reducing condition. |
