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Human IL15RA Protein, hFc Tag

Recombinant Human IL15RA Protein with C-terminal human Fc tag
5/5

¥389.00

货号:11348

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11348
产品全名:   人 IL15RA 蛋白
规格:   10/50/100 µg
基因符号   CD215
目标蛋白:    IL15RA
UNIPROT ID:    Q13261
描述:   Recombinant Human IL15RA Protein with C-terminal human Fc tag
背景:     This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 44.5 kDa after removal of the signal peptide.The apparent molecular mass of IL15RA-hFc is approximately 70 kDa due to glycosylation.
分子特征:   IL15RA(Ile31-Thr205) hFc(Glu99-Ala330)
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human IL15RA Protein, hFc Tag on SDS-PAGE under reducing condition.
           引用文献