武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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Human IGF-1R Protein, His Tag

Recombinant human IGF-1R protein with C-terminal 6XHis tag
5/5

$415.00

货号:11598

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11598
产品全名:   人 IGF-1R 蛋白
规格:   10/50/100 µg
基因符号   CD221;IGFIR;IGFR;JTK13
目标蛋白:    IGF-1R
UNIPROT ID:    P08069
描述:   Recombinant human IGF-1R protein with C-terminal 6xHis tag
背景:     This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 103.7 kDa after removal of the signal peptide. The apparent molecular mass of IGF-1R-His is approximately 130-150 kDa due to glycosylation.
分子特征:   IGF-1R(Glu31-Asn932) 6×His tag
纯化:   The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human IGF-1R Protein, His Tag on SDS-PAGE under reducing condition.
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