武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

微信:Neweast Biosciences

咨询:027 – 63497286 

Human GUCY2C Protein, His Tag

Recombinant human GUCY2C protein with C-terminal 6XHis tag
5/5

$479.00

货号:11252

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11252
产品全名:   人 GUCY2C 蛋白
规格:   10/50/100 µg
基因符号   DIAR6;GC-C;GUC2C;MECIL;MUCIL;STAR
目标蛋白:    GUCY2C
UNIPROT ID:    P25092
描述:   Recombinant human GUCY2C protein with C-terminal 6xHis tag
背景:     This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive). [provided by RefSeq, Nov 2016]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 46.8 kDa after removal of the signal peptide. The apparent molecular mass of GUCY2C-His is approximately 55-130 kDa due to glycosylation.
分子特征:   GUCY2C(Ser24-Gln430) 6×His tag
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human GUCY2C Protein, His Tag on SDS-PAGE under reducing condition.

Figure 2. ELISA plate pre-coated by 1 µg/ml (100 µl/well) Human GUCY2C protein, His Tag (11252) can bind Anti-GUCY2C Neutralizing antibody 28073 in a linear range of 3.2-400 ng/mL.
           引用文献