武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

微信:Neweast Biosciences

咨询:027 – 63497286 

Human GNRHR Protein, hFc Tag

Recombinant Human GNRHR Protein with C-terminal human Fc tag
5/5

$550.00

货号:11646

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11646
产品全名:   人 GNRHR 蛋白
规格:   10/50/100 µg
基因符号   GNRHR1;GRHR;HH7;LHRHR;LRHR
目标蛋白:    GNRHR
UNIPROT ID:    P30968
描述:   Recombinant Human GNRHR Protein with C-terminal human Fc tag
背景:     This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. [provided by RefSeq, Jul 2008]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 30.2 kDa after removal of the signal peptide.The apparent molecular mass of GNRHR-hFc is approximately 35-55 kDa due to glycosylation.
分子特征:   GNRHR(Met1-Arg38) hFc(Glu99-Ala330)
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human GNRHR Protein, hFc Tag on SDS-PAGE under reducing condition.
           引用文献