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Human GFRAL Protein, His Tag

Recombinant human GFRAL protein with C-terminal 6XHis tag
5/5

$479.00

货号:11417

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11417
产品全名:   人 GFRAL 蛋白
规格:   10/50/100 µg
基因符号   bA360D14.1;C6orf144;GRAL;UNQ9356
目标蛋白:    GFRAL
UNIPROT ID:    Q6UXV0
描述:   Recombinant human GFRAL protein with C-terminal 6xHis tag
背景:     Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099). Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways.[UniProtKB/Swiss-Prot Function]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 38.6 kDa after removal of the signal peptide. The apparent molecular mass of GFRAL-His is approximately 35-55 kDa due to glycosylation.
分子特征:   GFRAL(Ser19-Glu351) 6×His tag
纯化:   The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human GFRAL Protein, His Tag on SDS-PAGE under reducing condition.
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