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Human FZD4 Protein, hFc Tag

Recombinant Human FZD4 with C-terminal human Fc tag
5/5

¥415.00

货号:11414

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11414
产品全名:   人 FZD4 蛋白
规格:   10/50/100 µg
基因符号   CD344;EVR1;FEVR;Fz-4;Fz4;FZD4S;FzE4;GPCR;hFz4
目标蛋白:    FZD4
UNIPROT ID:    Q9ULV1
描述:   Recombinant Human FZD4 with C-terminal human Fc tag
背景:     This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 42.4 kDa after removal of the signal peptide. The apparent molecular mass of FZD4-hFc is approximately 55-70 kDa due to glycosylation.
分子特征:   FZD4(Phe37-Glu180) hFc(Glu99-Ala330)
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human FZD4 Protein, hFc Tag on SDS-PAGE under reducing condition.
           引用文献