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Human FGFR4 Protein, His Tag

Recombinant Human FGFR4 Protein with C-terminal 6XHis tag
5/5

$389.00

货号:11389

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11389
产品全名:   人 FGFR4 蛋白
规格:   10/50/100 µg
基因符号   CD334;JTK2;TKF
目标蛋白:    FGFR4
UNIPROT ID:    P22455
描述:   Recombinant Human FGFR4 Protein with C-terminal 6xHis tag
背景:     The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis. This protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. [provided by RefSeq, Aug 2017]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 39.3 kDa after removal of the signal peptide.The apparent molecular mass of FGFR4-His is approximately 35-70 kDa due to glycosylation.
分子特征:   FGFR4(Leu22-Asp369) 6×His Tag
纯化:   The purity of the protein is greater than 90% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human FGFR4 Protein, His Tag on SDS-PAGE under reducing condition.
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