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Human FASLG Protein, hFc Tag

Recombinant human FASLG with N-terminal human Fc tag
5/5

¥479.00

货号:11732

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11732
产品全名:   人 FASLG 蛋白
规格:   10/50/100 µg
基因符号   ALPS1B;APT1LG1;APTL;CD95-L;CD95L;CD178;FASL;TNFSF6;TNLG1A
目标蛋白:    FASLG
UNIPROT ID:    P48023
描述:   Recombinant human FASLG with N-terminal human Fc tag
背景:     This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 43.0 kDa after removal of the signal peptide. The apparent molecular mass of hFc-FASLG is approximately 35-55kDa due to glycosylation.
分子特征:   hFc(Glu99-Ala330) FASLG(Pro134-Leu281)
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human FASLG Protein, N-hFc Tag on SDS-PAGE under reducing condition.
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