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Human EPHB2 Protein, His Tag

Recombinant human EPHB2 protein with C-terminal 6XHis tag
5/5

$389.00

货号:11427

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11427
产品全名:   人 EPHB2 蛋白
规格:   10/50/100 µg
基因符号   BDPLT22;CAPB;DRT;EK5;EPHT3;ERK;Hek5;PCBC;Tyro5
目标蛋白:    EPHB2
UNIPROT ID:    P29323
描述:   Recombinant human EPHB2 protein with C-terminal 6xHis tag
背景:     This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 58.9 kDa after removal of the signal peptide. The apparent molecular mass of EPHB2-His is approximately 55-70 kDa due to glycosylation.
分子特征:   EPHB2(Val19-Leu543) 6×His tag
纯化:   The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human EPHB2 Protein, His Tag on SDS-PAGE under reducing condition.
           引用文献