武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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Human DNAM-1 Protein, mFc-His Tag

Recombinant human DNAM-1 protein with C-terminal mouse Fc and 6XHis tag
5/5

$479.00

货号:11176

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11176
产品全名:   人 DNAM-1 蛋白
规格:   10/50/100 µg
基因符号   DNAM1;CD226;PTA1
目标蛋白:    DNAM-1
UNIPROT ID:    Q15762
描述:   Recombinant human DNAM-1 protein with C-terminal mouse Fc and 6xHis tag
背景:     This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 53.5 kDa after removal of the signal peptide.
分子特征:   DNAM-1(Glu19-Asn247) mFc(Pro99-Lys330) 6×His tag
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human DNAM-1 Protein, mFc-His Tag on SDS-PAGE under reducing condition.

Figure 2. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human DNAM-1, mFc-His tagged protein (11176) can bind Human CD155, hFc Tagged protein 11293 in a linear range of 0.128-32.88 ng/ml.
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