| 货号: 11531 |
| 产品全名: 人 CD63 蛋白 |
| 规格: 10/50/100 µg |
| 基因符号 CD63 antigen;ranulophysin;AMP-3;imp1;elanoma-associated antigen ME491;MA81H;cular melanoma-associated antigen;etraspanin-30;Tspan-30 |
| 目标蛋白: CD63 |
| UNIPROT ID: P08962 |
| 描述: Recombinant human CD63 protein with C-terminal human Fc tag |
| 背景: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012] |
| 物种/宿主: HEK293 |
| 分子量: The protein has a predicted molecular mass of 37.7 kDa after removal of the signal peptide. The apparent molecular mass of CD63-hFc is approximately 35-55 kDa due to glycosylation. |
| 分子特征: CD63(Ala103-Val203) hFc(Glu99-Ala330) |
| 纯化: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| 储存和运输: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Human CD63 Protein, hFc Tag on SDS-PAGE under reducing condition. |
