武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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Human CD3E Protein, hFc Tag

Recombinant human CD3E protein with C-terminal human Fc tag
5/5

$415.00

货号:11609

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11609
产品全名:   人 CD3E 蛋白
规格:   10/50/100 µg
基因符号   CD3e;T3E
目标蛋白:    CD3E
UNIPROT ID:    P07766
描述:   Recombinant human CD3E protein with C-terminal human Fc tag
背景:     The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 37.9 kDa after removal of the signal peptide. The apparent molecular mass of CD3E-hFc is approximately 35-55 kDa due to glycosylation.
分子特征:   CD3E(Asp23-Asp126) hFc(Glu99-Ala330)
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human CD3E Protein, hFc Tag on SDS-PAGE under reducing condition.
           引用文献