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Human B7-2 Protein, mFc-His Tag

Recombinant human B7-2 protein with C-terminal mouse Fc and 6XHis tag
5/5

$415.00

货号:11162

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11162
产品全名:   人 B7-2 蛋白
规格:   10/50/100 µg
基因符号   CD86;B7-2;B70;CD28LG2;LAB72;MGC34413
目标蛋白:    B7-2
UNIPROT ID:    P42081
描述:   Recombinant human B7-2 protein with C-terminal mouse Fc and 6xHis tag
背景:     This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 52.4 kDa after removal of the signal peptide.
分子特征:   B7-2(Leu26-Pro247) mFc(Pro99-Lys330) 6×His tag
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human B7-2 Protein, mFc-His Tag on SDS-PAGE under reducing condition.
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