武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

微信:Neweast Biosciences

咨询:027 – 63497286 

Human AGR2 Protein, hFc Tag

Recombinant human AGR2 protein with C-terminal human Fc tag
5/5

$569.00

货号:11571

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11571
产品全名:   人 AGR2 蛋白
规格:   10/50/100 µg
基因符号   AG-2;hAG-2;HPC8
目标蛋白:    AGR2
UNIPROT ID:    O95994
描述:   Recombinant human AGR2 protein with C-terminal human Fc tag
背景:     This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression. [provided by RefSeq, Mar 2017]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 44.0 kDa after removal of the signal peptide. The apparent molecular mass of AGR2-hFc is approximately 35-55 kDa due to glycosylation.
分子特征:   AGR2(Arg21-Leu175) hFc(Glu99-Ala330)
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human AGR2 Protein, hFc Tag on SDS-PAGE under reducing condition.
           引用文献