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Human ACVR1C Protein, hFc Tag

Recombinant Human ACVR1C Protein with C-terminal human Fc tag
5/5

¥389.00

货号:11892

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11892
产品全名:   人 ACVR1C 蛋白
规格:   10/50/100 µg
基因符号   ACVRLK7;ALK7
目标蛋白:    ACVR1C
UNIPROT ID:    Q8NER5
描述:   Recombinant Human ACVR1C Protein with C-terminal human Fc tag
背景:     ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 36.0 kDa after removal of the signal peptide. The apparent molecular mass of ACVR1C-hFc is approximately 35-70 kDa due to glycosylation.
分子特征:   ACVR1C(Leu22-Glu113) hFc(Glu99-Ala330)
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1.Human ACVR1C Protein, hFc Tag on SDS-PAGE under reducing condition.
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