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Human GRM2 Full Length Protein

Human GRM2 Full Length Protein-Synthetic Nanodisc
5/5

$30,000.00

货号:11116

规格: 50 μg

库存状态:3-4 weeks

           产品描述          
货号:   11116
产品全名:   人 GRM2 Full Length 蛋白
规格:   10/50/100 µg
基因符号   GLUR2; GPRC1B; mGlu2; MGLUR2
目标蛋白:    GRM2
UNIPROT ID:    Q14416
描述:   人 GRM2 full length protein-synthetic nanodisc
背景:     L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
物种/宿主:    HEK293
分子量:   The human full length GRM2 protein has a MW of 95.6 kDa
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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