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Human GPR77 Full Length Protein

Human GPR77 Full Length Protein-Synthetic Nanodisc
5/5

$30,000.00

货号:11050

规格: 50 μg

库存状态:3-4 weeks

           产品描述          
货号:   11050
产品全名:   人 GPR77 Full Length 蛋白
规格:   10/50/100 µg
基因符号   C5L2; GPF77; GPR77
目标蛋白:    C5AR2
UNIPROT ID:    Q9P296
描述:   人 GPR77 full length protein-synthetic nanodisc
背景:     This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
物种/宿主:    HEK293
分子量:   The human full length C5AR2 protein has a MW of 36.1 kDa
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure1. Elisa plates were pre-coated with Flag Tag GPR77-Nanodisc (0.2 µg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with GPR77-Nanodisc is 3.415ng/ml.

Figure2. Human GPR77-Nanodisc, Flag Tag on SDS-PAGE
           引用文献