武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

微信:Neweast Biosciences

咨询:027 – 63497286 

Human CXCR4 Full Length Protein

Human CXCR4 Full Length Protein-Synthetic Nanodisc
5/5

$30,000.00

货号:11055

规格: 50 μg

库存状态:In Stock

           产品描述          
货号:   11055
产品全名:   人 CXCR4 Full Length 蛋白
规格:   10/50/100 µg
基因符号   CD184; D2S201E; FB22; HM89; HSY3RR; LAP-3; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; WHIM; WHIMS
目标蛋白:    CXCR4
UNIPROT ID:    P61073
描述:   人 CXCR4 full length protein-synthetic nanodisc
背景:     A CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome.
物种/宿主:    HEK293
分子量:   The human full length CXCR4 protein has a MW of 39.7 kDa
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure1. Elisa plates were pre-coated with Flag Tag CXCR4-Nanodisc (0.2 µg/per well). Serial diluted anti-CXCR4 monoclonal antibody (28101) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-CXCR4 monoclonal antibody binding with CXCR4-Nanodisc is 2442ng/ml.

Figure2. Human CXCR4-Nanodisc, Flag Tag on SDS-PAGE
           引用文献