武汉费斯德生物科技有限公司是美国NewEast Biosciences在中国的办事处。NewEast Biosciences 在十二年前率先研发俩种独特的抗体。这俩种抗体仅仅识别活性的GTP酶或者突变的Oncogene。 GTP酶涉及(1)响应细胞表面受体激活的信号转导,包括跨膜受体,例如介导味觉、嗅觉和视觉的那些,(2)核糖体的蛋白质生物合成,(3)调节细胞分化、增殖、分裂和运动,(4)蛋白质通过膜的易位,(5)细胞内囊泡的运输,以及囊泡介导的分泌和摄取,通过GTP酶控制囊泡外壳组装。Oncogene侧是诱发癌症的基因。
我公司将向你提供以下的独一无二的三种抗体或者试剂盒: (1) 仅识别 GTP酶的活性构型的产品, 它可以让你能够量化GTP酶在细胞中的活性和分布。(2) 识别突变 Oncogene蛋白, 但不认识相应野生型的抗体。 (3) 对 cAMP 和 cGMP 具有超亲和力(无需乙酰化)ELISA检测试剂盒。这些产品被将近一千篇同行评议的文章所引用。
¥2,800.00
产品名称: BRCA2(352-643) |
货号: 26364-1 |
基因符号: BRCA2, BRCC2, FAD1,FCD, BROVCA2, PNCA2 |
描述: BRCA2(352-643) 小鼠单抗 |
背景: BRCA2 is a human tumor suppressor gene. Its protein, also called by the synonym breast cancer type 2 susceptibility protein, is responsible for repairing DNA. Mutations of BRCA2 can cause an increased risk of breast cancer. In addition to breast cancer in men and women, mutations in BRCA2 also lead to an increased risk of ovarian, Fallopian tube, prostate, and pancreatic cancers, as well as malignant melanoma. |
免疫原 : Purified BRCA2(352-643) protein, human origin. |
经过测试的应用: ELISA, WB, IHC |
推荐稀释比: ELISA: 1:1000-1:2000 WB: 1:500-1:1000 IHC: 1:50-1:100 |
Concentration: 1 mg/ml |
种属反应性: Mouse |
形式: Liquid |
克隆性: Monoclonal |
亚型: IgG |
纯化: Purified from ascites |
成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
种属反应性: Recognizes BRCA2(352-643) of vertebrates. |
储存条件: Store at -20°C. Avoid repeated freezing and thawing |
蛋白质印迹: Purified His-tagged BRCA2(352-643) protein (lane1), His-tagged BRCA2 (1475-1748) protein(lane2), His-tagged BRCA2 (2213-2543) protein(lane3) and His-tagged BRCA2 (2793-3030) protein (lane4) were blotted with Anti-BRCA2(352-643) monoclonal antibody (货号:26364-1). Immunofluorescence: HEK293T cells was transfected with pCDNA3-GFP-BRCA2(352-643) plasmid, then fixed and stained with Anti-BRCA2(352-643) monoclonal antibody (货号:26364-1). |