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ASGR1 (DMC688) IgG1 Chimeric mAb

Anti-ASGR1 (DMC688) IgG1 Chimeric Monoclonal Antibody
5/5

¥445.00

货号:28286

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   28286
产品全名:   ASGR1(DMC688) IgG1 Chimeric 单抗
基因符号   ASGPR; ASGPR1; CLEC4H1; HL-1
描述:   ASGR1 antibody(DMC688) IgG1 Chimeric 单抗
背景:   This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B; and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits; which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq; Jan 2011]
经过测试的应用:   Flow Cyt
推荐稀释比:   Flow Cyt 1:100
种属反应性:   Rabbit
亚型:   Rabbit:Human Fc chimeric IgG1
纯化:   Purified from cell culture supernatant by affinity chromatography
种属反应性:   人 ASGR1
成分:   Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-ASGR1(DMC688) on Expi293 cells transfected with human ASGR1(Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
           引用文献