武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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ZNF395 Rabbit pAb

Anti-ZNF395 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S214378

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S214378
产品全名:   ZNF395 兔多抗
基因符号   PBF; PRF1; HDBP2; PRF-1; HDBP-2; HDRF-2; Si-1-8-14
UNIPROT ID:   Q9H8N7 (Gene Accession – NP_061130 )
背景:   Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF395 (Zinc finger protein 395), also known as PBF (Papillomavirus-binding factor) and HDBP2 (Huntington disease gene regulatory region-binding protein 2), is a 513 amino acid protein that contains one C2H2-type zinc finger. ZNF395 binds to the 3?-CCGG-5? sequence within the papillomavirus promoter adjacent to a RUNX1-binding motif. It has also been established that ZNF395 binds to a seven base pair region within the Huntington’s disease (HD) gene promoter, an essential element for HD gene expression. ZNF395 is widely expressed and probably shuttles between the nucleus and cytoplasm.
抗原:   Synthetic peptide of human ZNF395
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 50-200; ELISA: 2000-5000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human ovarian cancer tissue using 214378(ZNF395 Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with the synthetic peptide and then with 214378(Anti-ZNF395 Antibody) at dilution 1/40.
           引用文献