武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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ZFAND5 Rabbit pAb

Anti-ZFAND5 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S218043

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S218043
产品全名:   ZFAND5 兔多抗
基因符号   ZA20D2; ZNF216; ZFAND5A
UNIPROT ID:   O76080 (Gene Accession – BC011018 )
背景:   Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.
抗原:   Full length fusion 蛋白
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   IHC: 25-100;WB: 500-2000;ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Signal Transduction, Epigenetics and Nuclear Signaling, Cancer
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 218043(ZFAND5 Antibody) at a dilution of 1/35(Cytoplasm or Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 218043(Anti-ZFAND5 Antibody) at dilution 1/35.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 218043(Anti-ZFAND5 Antibody) at a dilution of 1/35.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with fusion protein and then with D223600(Anti-ZFAND5 Antibody) at dilution 1/35.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: Mouse fat tissue lysate;
Primary antibody: 218043(ZFAND5 Antibody) at dilution 1/500;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 1 minute
           引用文献