武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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XPO4 Rabbit mAb

Anti-XPO4 Rabbit Monoclonal Antibody
5/5

¥2,850.00

货号:N262197

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N262197
产品全名:   XPO4 兔单克隆抗体
基因符号   exp4
UNIPROT ID:   Q9C0E2
背景:   Mediates the nuclear export of proteins (cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO4 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
抗原:   A synthetic peptide of human Exportin 4
经过测试的应用:   WB,IP
推荐稀释比:   WB: 1/500-1/1000 IP: 1/20
种属反应性:   Rabbit
克隆性:   Rabbit Monoclonal
克隆编号:   R09-1A2
分子量:   Calculated MW: 130 kDa; Observed MW: 130 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human,Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Exportin 4 in MCF-7, C6 lysates using XPO4 antibody.
           引用文献