武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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VHL Rabbit pAb

Anti-VHL Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S216875

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S216875
产品全名:   VHL 兔多抗
基因符号   RCA1; VHL1; pVHL; HRCA1
UNIPROT ID:   P40337 (Gene Accession – BC058831 )
背景:   This gene encodes a component of a ubiquitination complex. The encoded protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. In addition to oxygen-related gene expression, this protein plays a role in many other cellular processes including cilia formation, cytokine signaling, regulation of senescence, and formation of the extracellular matrix. Variants of this gene are associated with von Hippel-Lindau syndrome, pheochromocytoma, erythrocytosis, renal cell carcinoma, and cerebellar hemangioblastoma.
抗原:   Fusion protein of human VHL
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   IHC: 50-200;WB: 500-2000;ELISA: 2000-5000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling, Cancer, Cardiovascular, Metabolism, Cell Biology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human breast cancer tissue using 216875(VHL Antibody) at a dilution of 1/40(Cytoplasm and Nucleus).

Immunohistochemistry analysis of paraffin-embedded Human colorectal cancer tissue using 216875(Anti-VHL Antibody) at a dilution of 1/40.

Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane: Human fetal brain tissue lysate;
Primary antibody: 216875(VHL Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 1 second
           引用文献