| 货号: S221592 |
| 产品全名: USP32 兔多抗 |
| 基因符号 USP10; NY-REN-60 |
| UNIPROT ID: Q8NFA0 (Gene Accession – NP_115971 ) |
| 背景: The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP32 (ubiquitin specific peptidase 32), also known as NY-REN-60, is a 1,604 amino acid protein that contains one DUSP domain and three EF-hand calcium binding domains. Localized to membranes in a lipid-anchored fashion and expressed in all normal tissues, USP32 catalyzes the conversion of a ubiquitin C-terminal thioester to a free ubiquitin and a thiol, a reaction that may influence several cellular processes. |
| 抗原: Synthetic peptide of human USP32 |
| 经过测试的应用: ELISA, IHC |
| 推荐稀释比: IHC: 25-100; ELISA: 5000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Epigenetics and Nuclear Signaling, Cell Biology |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 221592(USP32 Antibody) at a dilution of 1/20(Cytoplasm and Cell membrane). | 
In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the synthetic peptide and then with 221592(Anti-USP32 Antibody) at dilution 1/20. | 
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using 221592(Anti-USP32 Antibody) at a dilution of 1/20. | 
In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with synthetic peptide and then with D263244(Anti-USP32 Antibody) at dilution 1/20. |
|
