武汉费斯德生物科技有限公司是美国NewEast Biosciences在中国的办事处。NewEast Biosciences 在十二年前率先研发俩种独特的抗体。这俩种抗体仅仅识别活性的GTP酶或者突变的Oncogene。 GTP酶涉及(1)响应细胞表面受体激活的信号转导,包括跨膜受体,例如介导味觉、嗅觉和视觉的那些,(2)核糖体的蛋白质生物合成,(3)调节细胞分化、增殖、分裂和运动,(4)蛋白质通过膜的易位,(5)细胞内囊泡的运输,以及囊泡介导的分泌和摄取,通过GTP酶控制囊泡外壳组装。Oncogene侧是诱发癌症的基因。
我公司将向你提供以下的独一无二的三种抗体或者试剂盒: (1) 仅识别 GTP酶的活性构型的产品, 它可以让你能够量化GTP酶在细胞中的活性和分布。(2) 识别突变 Oncogene蛋白, 但不认识相应野生型的抗体。 (3) 对 cAMP 和 cGMP 具有超亲和力(无需乙酰化)ELISA检测试剂盒。这些产品被将近一千篇同行评议的文章所引用。
¥2,850.00
货号: N263029 |
产品全名: Trk B 兔单克隆抗体 |
基因符号 Tkrb; trkB; trk-B; GP145-TrkB/GP95-TrkB |
UNIPROT ID: P15209 |
背景: Receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity. Receptor for BDNF/brain-derived neurotrophic factor and NTF4/neurotrophin-4. Alternatively can also bind NTF3/neurotrophin-3 which is less efficient in activating the receptor but regulates neuron survival through NTRK2. |
抗原: Recombinant protein of mouse TrkB |
经过测试的应用: WB,IHC-P,IP |
推荐稀释比: WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20 |
种属反应性: Rabbit |
克隆性: Rabbit Monoclonal |
克隆编号: R03-4C7 |
分子量: Calculated MW: 92 kDa; Observed MW: 90-140 kDa |
亚型: IgG |
纯化: Affinity Purified |
种属反应性: Mouse,Rat |
成分: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
研究领域: Neuroscience&Trk |
储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
![]() Western blot analysis of TrkB in mouse brain, rat brain lysates using Trk B antibody. |